{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T06:30:24Z","timestamp":1781332224135,"version":"3.54.1"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T00:00:00Z","timestamp":1750032000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T00:00:00Z","timestamp":1750032000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Hemodialysis International"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>It has been suggested that ventricular strain measurements may be impaired in chronic hemodialysis patients despite having no history of heart disease. The aim of this study is to investigate whether ventricular strain parameters can be used to detect subclinical cardiac dysfunction in hemodialysis patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In our study, 47 patients under the age of 65\u2009years with no known history of cardiac or valvular disease and receiving chronic hemodialysis treatment for at least 1\u2009year were compared with an age\u2010 and sex\u2010matched control group of 29 healthy individuals. Transthoracic echocardiography was used to evaluate parameters such as global longitudinal strain, right ventricular global longitudinal strain, and left ventricular diastolic diameter. Differences between groups were analyzed by Student's\n                      <jats:italic>t<\/jats:italic>\n                      \u2010test and Mann\u2013Whitney\n                      <jats:italic>U<\/jats:italic>\n                      test.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The global longitudinal strain values of the hemodialysis group were significantly lower than those of the control group (\u221213.2\u2009\u00b1\u20093.91 vs. \u221222.1\u2009\u00b1\u20091.59,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Right ventricular global longitudinal strain (RV GLS) and left ventricular diastolic diameter were also significantly impaired in the hemodialysis group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). These results indicate the presence of subclinical cardiac dysfunction in hemodialysis patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Ventricular strain measurements may be impaired in chronic hemodialysis patients without a history of cardiovascular disease. Therefore, it is considered that ventricular strain measurements can be a useful method for the early detection of cardiac dysfunction in hemodialysis patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hdi.13272","type":"journal-article","created":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T00:25:06Z","timestamp":1750119906000},"page":"588-598","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Three Dimensional Speckle Tracking Echocardiography in Hemodialysis Patients"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3156-4883","authenticated-orcid":false,"given":"Serap","family":"Yadigar","sequence":"first","affiliation":[{"name":"Department of Nephrology Kartal Dr. L\u00fctfi K\u0131rdar City Hospital  \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0412-5292","authenticated-orcid":false,"given":"G\u00fcl\u00fcmser Sevgin","family":"Halil","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kartal Ko\u015fuyolu High Speciality Training and Research Hospital  \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8456-713X","authenticated-orcid":false,"given":"P\u0131nar","family":"\u00d6zdemir","sequence":"additional","affiliation":[{"name":"Department of Nephrology Kartal Dr. L\u00fctfi K\u0131rdar City Hospital  \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9504-8263","authenticated-orcid":false,"given":"Erman","family":"\u00d6zdemir","sequence":"additional","affiliation":[{"name":"Department of Nephrology Pendik State Hospital  \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1708-1807","authenticated-orcid":false,"given":"Ezgi G\u00fcltekin","family":"G\u00fcner","sequence":"additional","affiliation":[{"name":"Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital University of Health Sciences  \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0949-1734","authenticated-orcid":false,"given":"Abdurrahman Engin","family":"Demir","sequence":"additional","affiliation":[{"name":"Department of Aerospace Medicine, Institute of Defensive Health Sciences University of Health Sciences  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1687-7494","authenticated-orcid":false,"given":"Sukru Hakan","family":"Gunduz","sequence":"additional","affiliation":[{"name":"Department of Aerospace Medicine, Institute of Defensive Health Sciences University of Health Sciences  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1236-9177","authenticated-orcid":false,"given":"Banu \u015eahin","family":"Y\u0131ld\u0131z","sequence":"additional","affiliation":[{"name":"Department of Nephrology University of Health Sciences, Kartal Dr. L\u00fctfi K\u0131rdar City Hospital  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3502-4785","authenticated-orcid":false,"given":"Mustafa","family":"Y\u0131ld\u0131z","sequence":"additional","affiliation":[{"name":"Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital University of Health Sciences  \u0130stanbul 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