{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T22:59:22Z","timestamp":1768949962332,"version":"3.49.0"},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T00:00:00Z","timestamp":1750636800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T00:00:00Z","timestamp":1750636800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Hemodialysis International"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Arteriovenous (AV) fistulas are widely used in hemodialysis patients, but their most common complication is stenosis. Stiffness at the arterial site of the AV fistula is believed to contribute to stenosis. This study examines whether arterial stiffness can predict the development of AV fistula stenosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Arterial stiffness was assessed using brachial\u2010ankle pulse wave velocity (PWV). Chart reviews and laboratory records were analyzed. The diagnosis and intervention for AV fistula stenosis were performed using fistulography and percutaneous transluminal angioplasty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>\n                      A total of 80 patients were enrolled in the study. Over the 7\u2010year follow\u2010up period, 40 patients developed\n                      <jats:styled-content style=\"fixed-case\">AV<\/jats:styled-content>\n                      fistula stenosis. Univariate logistic regression analysis revealed that\n                      <jats:styled-content style=\"fixed-case\">AV<\/jats:styled-content>\n                      fistula stenosis was significantly associated with diabetes (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      : 4.68, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 1.19\u201318.34,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03), average monthly cholesterol level (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      : 1.02, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 1.00\u20131.04,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03), average monthly triglyceride level (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      : 1.01, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 1.00\u20131.01,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.02), and brachial\u2010ankle\n                      <jats:styled-content style=\"fixed-case\">PWV<\/jats:styled-content>\n                      (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      : 1.61, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 1.32\u20131.97,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01). In multivariate logistic regression analysis, only brachial\u2010ankle\n                      <jats:styled-content style=\"fixed-case\">PWV<\/jats:styled-content>\n                      remained significantly associated with\n                      <jats:styled-content style=\"fixed-case\">AV<\/jats:styled-content>\n                      fistula stenosis (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      : 1.72, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 1.34\u20132.22,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01). Receiver\u2010operating characteristic curve analysis identified 16.75\u2009m\/s as the optimal cutoff value of brachial\u2010ankle\n                      <jats:styled-content style=\"fixed-case\">PWV<\/jats:styled-content>\n                      for predicting the development of\n                      <jats:styled-content style=\"fixed-case\">AV<\/jats:styled-content>\n                      fistula stenosis. Patients with\n                      <jats:styled-content style=\"fixed-case\">PWV<\/jats:styled-content>\n                      \u2009&gt;\u200916.75\u2009m\/s had a significantly higher risk of developing\n                      <jats:styled-content style=\"fixed-case\">AV<\/jats:styled-content>\n                      fistula stenosis compared with those with a\n                      <jats:styled-content style=\"fixed-case\">PWV<\/jats:styled-content>\n                      \u2264\u200916.75\u2009m\/s (\n                      <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\n                      : 4.71, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 2.22\u20139.97,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Assessment of brachial\u2010ankle PWV can improve the prediction efficacy of AV fistula stenosis development in hemodialysis patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hdi.70001","type":"journal-article","created":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T04:28:07Z","timestamp":1750652887000},"page":"66-72","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association Between Pulse Wave Velocity and Arteriovenous Fistula Stenosis in Hemodialysis Patients"],"prefix":"10.1111","volume":"30","author":[{"given":"Kai\u2010Ni","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Nephrology Tainan Sinlau Hospital  Tainan 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