{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T22:47:58Z","timestamp":1790808478064,"version":"4.1.0"},"reference-count":39,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T00:00:00Z","timestamp":1756944000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T00:00:00Z","timestamp":1756944000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Hemodialysis International"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Double\u2010filtration plasmapheresis is an advanced extracorporeal blood purification technique that selectively removes pathogenic macromolecules based on molecular weight. Unlike conventional plasma exchange, double\u2010filtration plasmapheresis uses a two\u2010step filtration process to retain beneficial plasma components such as albumin, while eliminating harmful substances, thereby reducing the need for exogenous plasma replacement. Over the last few decades, double\u2010filtration plasmapheresis has gained prominence in the management of refractory autoimmune, neurological, metabolic, and renal diseases. This review systematically examines the therapeutic mechanisms, recent clinical advances, safety, limitations, and prospects of double\u2010filtration plasmapheresis.<\/jats:p>","DOI":"10.1111\/hdi.70026","type":"journal-article","created":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T06:33:23Z","timestamp":1757054003000},"page":"18-25","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Recent Progress in Double Filtration Plasmapheresis"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9555-5022","authenticated-orcid":false,"given":"Dan","family":"Li","sequence":"first","affiliation":[{"name":"Department of Nephrology Qingdao Central Hospital, University of Health and Rehabilitation Sciences  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqiang","family":"Liu","sequence":"additional","affiliation":[{"name":"Reproductive Medicine Center Qingdao Women and Children's Hospital  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhan","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Nephrology Qingdao Central Hospital, University of Health and Rehabilitation Sciences  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenxuan","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Nephrology Qingdao Central Hospital, University of Health and Rehabilitation Sciences  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,4]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.21705"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/1744-9987.13548"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.26442\/terarkh201890622-27"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/1744-9987.14194"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.22043"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/1744-9987.13749"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000528556"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000507615"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/1744-9987.12389"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.62347\/SSTO6670"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.21408"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0000000000000989"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2019.102313"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/1744-9987.13885"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.21037\/tp-22-322"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2017.09.028"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1159\/000506506"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2018.11.007"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.22032"},{"issue":"1","key":"e_1_2_11_21_1","first-page":"125","article-title":"Efficacy of Double Filtration Plasmapheresis Treatment in Acute Pancreatitis Associated With Severe Hypertriglyceridemia","volume":"19","author":"Yazan C. D.","year":"2023","journal-title":"Acta Endocrinologica"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12944-025-02448-2"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2023.1147675"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2018.12.002"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.21897"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.19046"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.21829"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2024.578463"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-024-03971-y"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/1744-9987.14039"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.19080\/JAICM.2020.10.555798"},{"key":"e_1_2_11_32_1","unstructured":"M.Naser M. M.Nasr andL. H.Shehata \u201cConvalescent Plasma Therapy for COVID\u201019 Is a Challenging Option \u201d(2021)."},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000023449"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2020.102928"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1744-9987.2012.01105.x"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2018.04.018"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijn.IJN_64_17"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfma.2024.02.006"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.22019"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1159\/000505613"}],"container-title":["Hemodialysis International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hdi.70026","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/hdi.70026","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hdi.70026","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T09:39:24Z","timestamp":1768901964000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hdi.70026"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,4]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1111\/hdi.70026"],"URL":"https:\/\/doi.org\/10.1111\/hdi.70026","archive":["Portico"],"relation":{},"ISSN":["1492-7535","1542-4758"],"issn-type":[{"value":"1492-7535","type":"print"},{"value":"1542-4758","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,4]]},"assertion":[{"value":"2025-06-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}