{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T22:25:54Z","timestamp":1785882354346,"version":"3.56.0"},"reference-count":51,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T00:00:00Z","timestamp":1770508800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T00:00:00Z","timestamp":1770508800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Hemodialysis International"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Hemodialysis, the primary treatment for chronic kidney disease, prolongs life but is frequently accompanied by physical and psychological symptoms that impair quality of life. Progressive muscle relaxation exercises offer a novel non\u2010pharmacological approach to symptom management. This study aimed to evaluate progressive muscle relaxation exercises on dialysis\u2010related symptoms (primary outcome) and quality of life (secondary outcome) in patients undergoing hemodialysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A randomized controlled pre\u2010test\u2013post\u2010test study was conducted between May and September 2025 in two dialysis units in eastern T\u00fcrkiye. Ninety\u2010two hemodialysis patients were randomly assigned to either an intervention group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200946) or a control group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200946). The intervention group received 24 sessions of progressive muscle relaxation exercises over 8\u2009weeks, while the control group received routine care. Data were collected at baseline and after the intervention using the dialysis symptom index and the Short Form\u201036 quality\u2010of\u2010life scale.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>\n                      The groups were similar in baseline. After the intervention, the progressive muscle relaxation exercises group demonstrated a significant reduction in symptom burden, with mean dialysis symptom index scores decreasing from 29.4\u2009\u00b1\u200913.3 to 16.3\u2009\u00b1\u20096.77 (\n                      <jats:italic>t<\/jats:italic>\n                      \u2009=\u20097.21,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Short\u2010Form\u201036 quality\u2010of\u2010life scores increased from 51.4\u2009\u00b1\u20099.83 to 65.8\u2009\u00b1\u200910.1 (\n                      <jats:italic>t<\/jats:italic>\n                      \u2009=\u20094.67,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), with significant improvements in physical functioning, vitality, pain, general health, and mental well\u2010being (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Progressive muscle relaxation exercises reduced dialysis\u2010related symptoms and improved quality of life in hemodialysis patients. Given its simplicity, non\u2010invasive nature, and low cost, it may be used as a complementary intervention in routine hemodialysis care. Further research should examine long\u2010term effects and broader clinical applicability.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hdi.70060","type":"journal-article","created":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T01:54:04Z","timestamp":1770602044000},"page":"394-406","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effect of Progressive Muscle Relaxation Exercises on Hemodialysis\u2010Related Symptoms and Quality of Life: A Randomized Controlled Trial"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5504-8058","authenticated-orcid":false,"given":"Sabri","family":"To\u011fluk","sequence":"first","affiliation":[{"name":"Vocational School of Health Services, Dialysis Program, Siirt University  Siirt Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4975-9558","authenticated-orcid":false,"given":"U\u011fur","family":"\u00d6ner","sequence":"additional","affiliation":[{"name":"Batman University Faculty of Health Sciences Department of Fundamentals Nursing  Batman Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,8]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136\u2010020\u201002508\u20103"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.51972\/tfsd.976364"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2025.1580689"},{"issue":"4","key":"e_1_2_9_5_1","first-page":"7","article-title":"The Effect of Progressive Muscle Relaxation Technique on Fatigue, Pain and Quality of Life in Dialysis Patients: A Clinical Trial Study","volume":"12","author":"Ghozhdi M. 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