{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T10:04:43Z","timestamp":1775815483971,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Hemodialysis International"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Patients with end\u2010stage renal disease (ESRD) undergoing chronic hemodialysis (HD) frequently report the sensation of prostration, tiredness, weakness, exhaustion, weariness, or fatigue after the hemodialysis treatment. This condition is defined as post\u2010dialysis fatigue and significantly impairs patients' ability to perform routine daily activities. The present study aims to investigate whether territorial or environmental factors such as differences in geographic areas are associated with the prevalence and characteristics of post\u2010dialysis fatigue and time to recovery after dialysis among chronic HD patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 465 patients from six Italian HD units, located in both northern and central Italy, were enrolled between January and December 2024. Exclusion criteria included a dialysis duration of less than 1\u2009year and a diagnosis of dementia, acute infectious disease, or active cancer. For each participant, demographic, clinical, and laboratory data were collected.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>The results showed that 61.5% of the patients reported suffering from post\u2010dialysis fatigue. The prevalence and characteristics of post\u2010dialysis fatigue, as well as the length of time to recovery after dialysis, varied significantly among the six HD units. Multivariate analyses revealed that the hemodialysis unit itself was the main variable significantly and independently associated with both post\u2010dialysis fatigue and time to recovery after dialysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our findings suggest that environmental factors such as differences in geographic areas are associated with the prevalence and characteristics of post\u2010dialysis fatigue and time to recovery after dialysis among chronic HD patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hdi.70065","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T23:32:46Z","timestamp":1773012766000},"page":"374-383","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dialysis Unit Differences in Post\u2010Dialysis Fatigue Prevalence and Characteristics and Time to Recovery After Dialysis"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1627-0235","authenticated-orcid":false,"given":"Maurizio","family":"Bossola","sequence":"first","affiliation":[{"name":"Servizio Emodialisi Universit\u00e0 Cattolica del Sacro Cuore  Roma Italy"},{"name":"Fondazione Policlinico Universitario A. Gemelli IRCCS  Roma Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annalisa","family":"Senatore","sequence":"additional","affiliation":[{"name":"Fondazione Policlinico Universitario A. Gemelli IRCCS  Roma Italy"},{"name":"Divisione di Nefrologia Universit\u00e0 Cattolica del Sacro Cuore  Roma Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Astrid","family":"Brys","sequence":"additional","affiliation":[{"name":"Department of Geriatric Medicine Ghent University Hospital  Ghent Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuele","family":"Parodi","sequence":"additional","affiliation":[{"name":"Dipartimento di Nefrologia Ospedale Civile  Alessandria Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tania","family":"Monteburini","sequence":"additional","affiliation":[{"name":"Dipartimento di Nefrologia Ospedale \u201cCarlo Urbani\u201d  Jesi Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Santarelli","sequence":"additional","affiliation":[{"name":"Dipartimento di Nefrologia Ospedale \u201cCarlo Urbani\u201d  Jesi Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Quaglia","sequence":"additional","affiliation":[{"name":"Dipartimento di Nefrologia Ospedale Civile  Alessandria Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vittorio","family":"Sirolli","sequence":"additional","affiliation":[{"name":"Dipartimento di Nefrologia Universit\u00e0 di Chieti  Chieti Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Bonomini","sequence":"additional","affiliation":[{"name":"Dipartimento di Nefrologia Universit\u00e0 di Chieti  Chieti Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilda","family":"Pepe","sequence":"additional","affiliation":[{"name":"Fondazione Policlinico Universitario A. 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Gemelli IRCCS  Roma Italy"},{"name":"Divisione di Chimica, Biochimica, e Biochimica Molecolare Universit\u00e0 Cattolica del Sacro Cuore  Roma Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,6]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/sdi.12468"},{"key":"e_1_2_12_3_1","doi-asserted-by":"crossref","unstructured":"M.Bossola C.Vulpio andL.Tazza \u201cFatigue in Chronic Dialysis Patients \u201d24 no.5(2011):550\u2013555.","DOI":"10.1111\/j.1525-139X.2011.00956.x"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.00040106"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2014.01.014"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/nep.12692"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2019.02.010"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.3758\/LB.37.1.1"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10865-005-4659-9"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/1478-7954-2-1"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/039139880402700409"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1963.03060120024016"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/geront\/9.3_Part_1.179"},{"issue":"1","key":"e_1_2_12_14_1","first-page":"67","article-title":"Presentazione del Beck Depression Inventory\u2010 Seconda Edizione (BDI\u2010II): conferma della struttura bifattoriale in un campione di popolazione italiana","volume":"12","author":"Montano A.","year":"2006","journal-title":"Psicoterapia Cognitiva e Comportamentale"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1053\/ajkd.1998.v31.pm9631846"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02897927"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2021.658974"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/1478-7954-5-5"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0284189"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/JNC.0000000000000025"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2024.1273151"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.2147\/PPA.S400996"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.70437"}],"container-title":["Hemodialysis International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hdi.70065","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/hdi.70065","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hdi.70065","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T09:31:20Z","timestamp":1775813480000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hdi.70065"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,6]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1111\/hdi.70065"],"URL":"https:\/\/doi.org\/10.1111\/hdi.70065","archive":["Portico"],"relation":{},"ISSN":["1492-7535","1542-4758"],"issn-type":[{"value":"1492-7535","type":"print"},{"value":"1542-4758","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,6]]},"assertion":[{"value":"2025-11-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}