{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T03:45:24Z","timestamp":1792035924282,"version":"4.4.0"},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001232","name":"Royal Australasian College of Physicians","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001232","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Hemodialysis International"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Hypothesis<\/jats:title>\n                    <jats:p>Patients receiving chronic dialysis have increased risks of postoperative mortality and morbidity. Studies have suggested that patients receving hemodiafiltration (HDF) compared to hemodialysis (HD) may benefit from improved cardiovascular health, reduced infections and better overall survival. This study aimed to determine if patients receving HDF had improved postoperative outcomes after elective surgery compared to patients receiving HD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Bi\u2010national population cohort study evaluated all incident and prevalent patients receiving chronic hemodialysis in Australia and New Zealand. Surgeries included upper gastrointestinal, anorectal, hernia surgery, cholecystectomy and appendectomy. The primary outcome was 30\u2010day all\u2010cause mortality. Secondary outcomes included cardiovascular and infective outcomes. As there was potential for data to be correlated with multiple surgeries clustered at the patient and centre level, a multi\u2010level mixed effects logistic regression model was used, with patient level covariates as fixed effects and dialysis centre as random intercepts, whereby patients were nested within centres.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      During the study period, there were 1750 surgeries in 1669 patients, of which 416 (23.8%) were receiving HDF. The median age was similar in both groups, as was the prevalence of comorbidities. Patients receiving HDF had received dialysis for a shorter period (0.9 vs. 2.3\u2009years,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). The 30\u2010day mortality rate was lower in patients receiving HDF than in those receiving HD (1.9 vs. 3.3%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.005). Using multi\u2010level mixed effects logistic regression, HDF was not associated with reduced mortality odds (OR 0.84, 95% CI 0.37\u20131.93) compared to patients receiving HD. Patients on HDF experienced a lower rate of a composite of infections (5.5 vs. 9.8%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.012), and required less blood transfusions (7.7 vs. 12.4%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.009). The occurrence of cardiovascular complications was not significantly different between the two groups (1.4 vs. 2.3%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.280).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The use of HDF was not associated with lower postoperative mortality odds but lower rates of infective complications compared to HD were observed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hdi.70072","type":"journal-article","created":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T05:29:42Z","timestamp":1775107782000},"page":"573-581","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of Hemodiafiltration and Hemodialysis on Postoperative Mortality in Patients With Kidney Failure"],"prefix":"10.1111","volume":"30","author":[{"given":"Dharmenaan","family":"Palamuthusingam","sequence":"first","affiliation":[{"name":"Metro North Kidney Health Service, Royal Brisbane and Women's Hospital  Herston Queensland Australia"},{"name":"Faculty of Medicine University of Queensland  St Lucia Queensland Australia"},{"name":"School of Medicine Griffith University  Southport Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmel M.","family":"Hawley","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Queensland  St Lucia Queensland Australia"},{"name":"Metro South Kidney and Transplant Services, Princess Alexandra Hospital  Woolloongabba Queensland Australia"},{"name":"Australasian Kidney Trials Network (AKTN) University of Queensland  Brisbane Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elaine M.","family":"Pascoe","sequence":"additional","affiliation":[{"name":"Centre for Health Services Research University of Queensland  St Lucia Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David Wayne","family":"Johnson","sequence":"additional","affiliation":[{"name":"Metro South Kidney and Transplant Services, Princess Alexandra Hospital  Woolloongabba Queensland Australia"},{"name":"Australasian Kidney Trials Network (AKTN) University of Queensland  Brisbane Australia"},{"name":"Translational Research Institute  Brisbane Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Wolley","sequence":"additional","affiliation":[{"name":"Metro North Kidney Health Service, Royal Brisbane and Women's Hospital  Herston Queensland Australia"},{"name":"Faculty of Medicine University of Queensland  St Lucia Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"McDonald","sequence":"additional","affiliation":[{"name":"Central Northern Adelaide Renal and Transplantation Service, Royal Adelaide Hospital  Adelaide South Australia Australia"},{"name":"Australia and New Zealand Dialysis and Transplant Registry (ANZDATA) South Australia Health and Medical Research Institute (SAHMRI)  Adelaide South Australia Australia"},{"name":"Adelaide Medical School The University of Adelaide  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil","family":"Boudville","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Western Australia  Perth Western Australia Australia"},{"name":"Sir Charles Gairdner Hospital, Hospital Ave  Nedlands Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew D.","family":"Jose","sequence":"additional","affiliation":[{"name":"Department of Nephrology Royal Hobart Hospital  Hobart Tasmania Australia"},{"name":"School of Medicine  Hobart Tasmania Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9540-2253","authenticated-orcid":false,"given":"Girish","family":"Talaulikar","sequence":"additional","affiliation":[{"name":"Renal Services, ACT Health  Canberra Australians Capital Territory Australia"},{"name":"School of Medicine Australian National University (ANU)  Canberra Australian Capital Territory Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas B.","family":"Cross","sequence":"additional","affiliation":[{"name":"Department of Nephrology Te Whatu Ora Waitaha Canterbury, Christchurch Hospital  Christchurch New Zealand"},{"name":"Christchurch School of Medicine University of Otago  Christchurch New Zealand"},{"name":"New Zealand Clinical Research  Christchurch New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magid","family":"Fahim","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Queensland  St Lucia Queensland Australia"},{"name":"Metro South Kidney and Transplant Services, Princess Alexandra Hospital  Woolloongabba Queensland Australia"},{"name":"Metro North Health Service  Herston Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,1]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12882-021-02279-0"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0234402"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/imj.14168"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.2215\/cjn.10110917"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2304820"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/sdi.12200"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(24)01859-2"},{"key":"e_1_2_10_9_1","unstructured":"Australian Consortium for Classification Development (ACCD) The Australian Classification of Health Interventions (ACHI) \u2013 Eleventh Edition \u2010 Tabular List of Interventions and Alphabetic Index of 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