{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T01:53:56Z","timestamp":1791251636455,"version":"4.1.0"},"reference-count":68,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,5,24]],"date-time":"2026-05-24T00:00:00Z","timestamp":1779580800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,24]],"date-time":"2026-05-24T00:00:00Z","timestamp":1779580800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Hemodialysis International"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Needle phobia is a significant barrier to home HD adoption, affecting 20%\u201360% of adults andchildren. This comprehensive review explores the complexities of needle phobiain dialysis patients, examining its origins, mechanisms, and impact through patient experiences and coping strategies. The necessity of cannulation in home HD patients with an AV access can deter patients from adopting self\u2010care, yet mastering self\u2010cannulation can effectively help overcome needle phobia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Factors contributing to needle phobia include genetic predisposition, traumatic experiences, andchronic pain. The physiological response involves a diphasic reaction, with initial sympathetic activation followed by a parasympathetic surge, potentially leading to vasovagal syncope.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A holistic approach to managing needle\u2010related distress, addressing physiological pain, fear, and lack of control is proposed. This includes both pharmacological and non\u2010pharmacological methods, such as desensitization therapy, topical anesthetics, distraction techniques, and cognitive\u2010behavioral interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Systematic screening for needle phobia, education and targeted interventions can empower patientsand improve outcomes. Only then can we foster a culture of compassion, empathy, and personalized support, thereby transforming dialysis care and improving patient experiences.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hdi.70085","type":"journal-article","created":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T03:17:25Z","timestamp":1779679045000},"page":"651-658","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Demystifying Needle Phobia: Facilitating Home Hemodialysis Through Self\u2010Cannulation: A Literature Review and Case Series"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-8029-9351","authenticated-orcid":false,"given":"Maria C.","family":"Bermudez","sequence":"first","affiliation":[{"name":"Geisinger Medical Center  Danville Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osama","family":"El Shamy","sequence":"additional","affiliation":[{"name":"Renal, Electrolyte, and Hypertension Division Hospital of the University of Pennsylvania, Perelman School of Medicine at the University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,24]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xkme.2020.04.004"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/ajkd.2003.50047"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0276814"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cegh.2023.101257"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0253048"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2014.06.024"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.34067\/KID.0000000000000560"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/MNH.0000000000001033"},{"key":"e_1_2_4_10_1","unstructured":"Centers for Medicare & Medicaid Services Department of Health and Human Services \u201cCondition: Patients' Rights. 42 CFR 494.70\u201d https:\/\/www.ecfr.gov\/current\/title\u201042\/part\u2010494\/section\u2010494.70. Last accessed August 24 2025."},{"key":"e_1_2_4_11_1","unstructured":"Centers for Medicare & Medicaid Services Department of Health and Human Services \u201cCondition: Patient Assessment. 42 CFR 494.80\u201d https:\/\/www.ecfr.gov\/current\/title\u201042\/part\u2010494\/section\u2010494.80. Last accessed August 24 2025."},{"key":"e_1_2_4_12_1","unstructured":"Centers for Medicare & Medicaid Services Department of Health and Human Services \u201cCondition: Patient Plan of Care. 42 CFR 494.90\u201d https:\/\/www.ecfr.gov\/current\/title\u201042\/part\u2010494\/section\u2010494.90. Last accessed August 24 2025."},{"key":"e_1_2_4_13_1","volume-title":"2019 USRDS Annual Data Report: Epidemiology of Kidney Disease in the United States","author":"United States Renal Data System","year":"2019"},{"key":"e_1_2_4_14_1","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"American Psychiatric Association","year":"1980"},{"issue":"2","key":"e_1_2_4_15_1","first-page":"169","article-title":"Needle Phobia: A Neglected Diagnosis","volume":"41","author":"Hamilton J. G.","year":"1995","journal-title":"Journal of Family Practice"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.4161\/hv.29599"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12630\u2010009\u20109072\u20105"},{"key":"e_1_2_4_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/2377960818759442"},{"key":"e_1_2_4_19_1","doi-asserted-by":"publisher","DOI":"10.1161\/hc3301.094910"},{"key":"e_1_2_4_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10286\u2010005\u20100245\u2010z"},{"key":"e_1_2_4_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0005\u20107967(94)90161\u20109"},{"issue":"2","key":"e_1_2_4_22_1","first-page":"83","article-title":"Self\u2010Reported Fears of Hospitalized School\u2010Age Children","volume":"9","author":"Hart D.","year":"1994","journal-title":"Journal of Pediatric Nursing"},{"issue":"2","key":"e_1_2_4_23_1","first-page":"147","article-title":"Factors Influencing the Fear of Needles Among Students of Medicine and Pharmacy","volume":"34","author":"Milovanovi'c B.","year":"2017","journal-title":"Acta Facultatis Medicae Naissensis"},{"key":"e_1_2_4_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12888\u2010024\u201005757\u20105"},{"key":"e_1_2_4_25_1","doi-asserted-by":"publisher","DOI":"10.1177\/112972981880158"},{"key":"e_1_2_4_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13123577"},{"key":"e_1_2_4_27_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2006.02.181"},{"key":"e_1_2_4_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467\u2010016\u20103382\u20109"},{"key":"e_1_2_4_29_1","doi-asserted-by":"publisher","DOI":"10.1177\/2054358121993995"},{"key":"e_1_2_4_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjhp.12303"},{"key":"e_1_2_4_31_1","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"Jeste D. V.","year":"2022"},{"key":"e_1_2_4_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2013.03.011"},{"key":"e_1_2_4_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpsycho.2010.05.007"},{"key":"e_1_2_4_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/psyp.12900"},{"key":"e_1_2_4_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2009.04.008"},{"key":"e_1_2_4_36_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003\u20104819\u201089\u20103\u2010403"},{"key":"e_1_2_4_37_1","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.145.10.1207"},{"key":"e_1_2_4_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(61)90051-1"},{"key":"e_1_2_4_39_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_4_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.janxdis.2005.06.005"},{"key":"e_1_2_4_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)58098-2"},{"key":"e_1_2_4_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/jorc.12391"},{"key":"e_1_2_4_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2023.09.011"},{"key":"e_1_2_4_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755\u20106686.2013.12039.x"},{"key":"e_1_2_4_45_1","doi-asserted-by":"crossref","first-page":"S320","DOI":"10.1016\/j.ekir.2023.02.718","article-title":"World Congress of Nephrology 2023\u20100501. Development and Validation of a Screening Tool for Identification of Needle Fear in Dialysis Patients\u2014Measuring Needle Fear Tool","volume":"8","author":"Radisic G.","year":"2023","journal-title":"Kidney International Reports"},{"key":"e_1_2_4_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/hdi.12340"},{"key":"e_1_2_4_47_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD005179.pub2"},{"key":"e_1_2_4_48_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2025.1642988"},{"key":"e_1_2_4_49_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0230372"},{"key":"e_1_2_4_50_1","unstructured":"A. M.Sharifnia G.Chu E.Manias P. M.Davidson andR.Fernandez \u201cComparative Analysis of the Effectiveness of Pharmacological and Non\u2010Pharmacological Interventions on Arteriovenous Fistula Cannulation\u2010Related Pain in Patients Receiving Hemodialysis: A Systematic Review and Network Meta\u2010Analysis\u201d."},{"key":"e_1_2_4_51_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/8383021"},{"key":"e_1_2_4_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2025.105123"},{"key":"e_1_2_4_53_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijms.8.623"},{"key":"e_1_2_4_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctim.2020.102440"},{"key":"e_1_2_4_55_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.09910917"},{"key":"e_1_2_4_56_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.05230419"},{"key":"e_1_2_4_57_1","doi-asserted-by":"publisher","DOI":"10.1111\/sdi.12979"},{"key":"e_1_2_4_58_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13063\u2010019\u20103773\u2010x"},{"key":"e_1_2_4_59_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0285156"},{"key":"e_1_2_4_60_1","doi-asserted-by":"publisher","DOI":"10.1111\/papt.12098"},{"key":"e_1_2_4_61_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.03900417"},{"key":"e_1_2_4_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctim.2015.03.001"},{"key":"e_1_2_4_63_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12165390"},{"key":"e_1_2_4_64_1","doi-asserted-by":"publisher","DOI":"10.1097\/MNH.0000000000001121"},{"key":"e_1_2_4_65_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525\u2010139X.2007.00335.x"},{"key":"e_1_2_4_66_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfv260"},{"key":"e_1_2_4_67_1","doi-asserted-by":"publisher","DOI":"10.2147\/JPR.S132409"},{"key":"e_1_2_4_68_1","doi-asserted-by":"publisher","DOI":"10.1177\/1129729819891026"},{"key":"e_1_2_4_69_1","unstructured":"National Institute for Health and Care Excellence \u201cUltrasound\u2010Guided Cannulation of Arteriovenous Fistulae. NICE Guideline IPG559\u201d(2015)."}],"container-title":["Hemodialysis International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hdi.70085","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/hdi.70085","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hdi.70085","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T01:46:40Z","timestamp":1791251200000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hdi.70085"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,24]]},"references-count":68,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1111\/hdi.70085"],"URL":"https:\/\/doi.org\/10.1111\/hdi.70085","archive":["Portico"],"relation":{},"ISSN":["1492-7535","1542-4758"],"issn-type":[{"value":"1492-7535","type":"print"},{"value":"1542-4758","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,24]]},"assertion":[{"value":"2025-12-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}