{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T20:04:50Z","timestamp":1774728290180,"version":"3.50.1"},"reference-count":33,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,3,13]],"date-time":"2013-03-13T00:00:00Z","timestamp":1363132800000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Headache"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:p>\n                    Reversible cerebral vasoconstriction syndrome (\n                    <jats:styled-content style=\"fixed-case\">RCVS<\/jats:styled-content>\n                    ) is a cerebrovascular disorder with a clinical picture that continues to be refined. It has presented to multiple subspecialties over the past several decades, bringing with it many questions regarding risk factors, diagnosis, and management. Answers have been forthcoming but many questions remain.\n                    <jats:styled-content style=\"fixed-case\">RCVS<\/jats:styled-content>\n                    presents with recurrent, secondary thunderclap headaches and predominantly affects young women. The mechanism of vasoconstriction is unclear, but there has been speculation regarding a hyperadrenergic state. Diagnosis requires physician awareness, vascular imaging, and knowledge of the differential. The hallmark of its diagnosis is reversibility. Management is empiric, usually with calcium\u2010channel blockers, as there are no controlled treatment trials for\n                    <jats:styled-content style=\"fixed-case\">RCVS<\/jats:styled-content>\n                    . Randomized controlled trials are needed.\n                  <\/jats:p>","DOI":"10.1111\/head.12040","type":"journal-article","created":{"date-parts":[[2013,3,14]],"date-time":"2013-03-14T09:11:26Z","timestamp":1363252286000},"page":"570-576","source":"Crossref","is-referenced-by-count":29,"title":["Reversible Cerebral Vasoconstriction Syndrome"],"prefix":"10.1111","volume":"53","author":[{"given":"Holly","family":"Yancy","sequence":"first","affiliation":[{"name":"Department of Neurology Mayo Clinic  Phoenix AZ USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joyce K.","family":"Lee\u2010Iannotti","sequence":"additional","affiliation":[{"name":"Department of Neurology Mayo Clinic  Phoenix AZ USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Todd J.","family":"Schwedt","sequence":"additional","affiliation":[{"name":"Department of Neurology Mayo Clinic  Phoenix AZ USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David 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