{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T23:13:29Z","timestamp":1768778009187,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,4,10]],"date-time":"2013-04-10T00:00:00Z","timestamp":1365552000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Headache"],"published-print":{"date-parts":[[2013,6]]},"abstract":"\n Objective<\/jats:title>\n \n To identify symptoms that may predict postural tachycardia syndrome (\n POTS<\/jats:styled-content>\n ) among adolescent patients with headache and lightheadedness referred for tilt table testing.\n <\/jats:p>\n <\/jats:sec>\n \n Background<\/jats:title>\n \n Individuals with\n POTS<\/jats:styled-content>\n can have a variety of symptoms that impair quality of life. The specific symptoms that help to distinguish the\n POTS<\/jats:styled-content>\n patient in an adolescent headache population have not been determined.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n A group of symptoms was compared among 70 adolescent patients with headache and lightheadedness referred to a pediatric headache clinic for tilt table testing. Every patient completed a symptom questionnaire prior to the tilt table test. The chi\u2010square test was used to compare questionnaire responses between patients found to have\n POTS<\/jats:styled-content>\n and those who did not have\n POTS<\/jats:styled-content>\n . Thirteen symptoms were analyzed. Symptoms that differed statistically between groups were further assessed for sensitivity, specificity, and diagnostic predictive values.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Thirty\u2010seven (53%) patients met diagnostic criteria for\n POTS<\/jats:styled-content>\n . Several symptoms differed between the patients found to have\n POTS<\/jats:styled-content>\n and those without\n POTS<\/jats:styled-content>\n . Headache type was not predictive. Vertigo and evening exacerbation of headaches had\n \n P<\/jats:styled-content>\n <\/jats:italic>\n values <.05 but did not meet significance after a statistical correction for multiple variables,\n \n P<\/jats:styled-content>\n <\/jats:italic>\n \u2009\u2264\u2009.004 (0.05\/13). New\u2010onset motion sickness, dizziness as a headache trigger, and orthostatic headaches had\n \n P<\/jats:styled-content>\n <\/jats:italic>\n values <.004 and were relatively sensitive and\/or specific for the\n POTS<\/jats:styled-content>\n diagnosis.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n While no single clinical symptom or headache type reliably establishes the\n POTS<\/jats:styled-content>\n diagnosis, several symptoms can help to distinguish the\n POTS<\/jats:styled-content>\n patient in an adolescent headache population.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/head.12103","type":"journal-article","created":{"date-parts":[[2013,4,10]],"date-time":"2013-04-10T16:59:53Z","timestamp":1365613193000},"page":"947-953","source":"Crossref","is-referenced-by-count":25,"title":["Symptoms Predictive of Postural Tachycardia Syndrome (\n POTS<\/scp>\n ) in the Adolescent Headache Patient"],"prefix":"10.1111","volume":"53","author":[{"given":"Geoffrey L.","family":"Heyer","sequence":"first","affiliation":[{"name":"Division of Pediatric Neurology Nationwide Children's Hospital Columbus OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin M.","family":"Fedak","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurology Nationwide Children's Hospital Columbus OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aggie L.","family":"LeGros","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Nationwide Children's Hospital Columbus OH 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