{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T13:33:50Z","timestamp":1790688830997,"version":"4.1.0"},"reference-count":72,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,2,10]],"date-time":"2014-02-10T00:00:00Z","timestamp":1391990400000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Headache"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:p>\n                    Individually, both obesity and headache are conditions associated with a substantial personal and societal impact. Recent data support that obesity is comorbid with headache in general and migraine specifically, as well as with certain secondary headache conditions such as idiopathic intracranial hypertension. In the current manuscript, we first briefly review the epidemiology of obesity and common primary and secondary headache disorders individually. This is followed by a systematic review of the general population data evaluating the association between obesity and headache in general, and then obesity and migraine and tension\u2010type headache disorders. Finally, we briefly discuss the data on the association between obesity and a common secondary headache disorder that is associated with obesity, idiopathic intracranial hypertension. Taken together, these data suggest that it is important for clinicians and patients to be aware of the headache\/migraine\u2010obesity association, given that it is potentially modifiable. Hypotheses for mechanisms of the obesity\u2010migraine association and treatment considerations for overweight and obese headache sufferers are discussed in the companion manuscript, as part\n                    <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content>\n                    of this topic.\n                  <\/jats:p>","DOI":"10.1111\/head.12296","type":"journal-article","created":{"date-parts":[[2014,2,10]],"date-time":"2014-02-10T16:17:17Z","timestamp":1392049037000},"page":"219-234","source":"Crossref","is-referenced-by-count":118,"title":["Obesity and Headache: Part\n                    <scp>I<\/scp>\n                    \u2013 A Systematic Review of the Epidemiology of Obesity and Headache"],"prefix":"10.1111","volume":"54","author":[{"given":"Nu Cindy","family":"Chai","sequence":"first","affiliation":[{"name":"Johns Hopkins University School of Medicine  Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann I.","family":"Scher","sequence":"additional","affiliation":[{"name":"USUHS  Bethesda MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhay","family":"Moghekar","sequence":"additional","affiliation":[{"name":"Johns Hopkins University School of Medicine  Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dale S.","family":"Bond","sequence":"additional","affiliation":[{"name":"Brown Alpert Medical School  Providence RI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. Lee","family":"Peterlin","sequence":"additional","affiliation":[{"name":"Johns Hopkins University School of Medicine  Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,2,10]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"1","article-title":"Physical status: The use and interpretation of anthropometry. Report of a WHO Expert Committee","volume":"854","author":"WHO Expert Committee","year":"1995","journal-title":"World Health Organ Tech Rep Ser"},{"key":"e_1_2_10_3_1","first-page":"51S","article-title":"Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults \u2013 the evidence report","volume":"6","author":"National Institutes of Health","year":"1998","journal-title":"Obes Res"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2007.505"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2010.186"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/75.6.971"},{"key":"e_1_2_10_7_1","first-page":"793","article-title":"Subcutaneous adipose tissue distribution in adolescent girls of four ethnic groups","volume":"19","author":"Malina RM","year":"1995","journal-title":"Int J Obes Relat Metab Disord"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/790654"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)15268-3"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181da9423"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/ejcn.2013.61"},{"key":"e_1_2_10_12_1","first-page":"A03","article-title":"Obesity and obesity\u2010related comorbidities in a Canadian first nation population","volume":"8","author":"Bruce SG","year":"2011","journal-title":"Prev Chronic Dis"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10194-012-0416-y"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.21710"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2012.02114.x"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2007.01288.x"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102411428953"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-004-6519-2"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-010-0146-2"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1249220"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2004.04167.x"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2001.041007646.x"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.5671\/ca.2012361s.71"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.42.9.1657"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.53.7.1468"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen,2012\u2010000962"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102410391488"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2005.00873.x"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2004.00681.x"},{"key":"e_1_2_10_30_1","first-page":"331","article-title":"Prevalence of chronic migraine headaches \u2013 United States","volume":"40","author":"Centers for Disease Control and Prevention. Morbidity and Mortality Weekly Report","year":"1991","journal-title":"MMWR"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.1996.3608466.x"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2000.00071.x"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1992.03480010072027"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a114892"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-009-0066-1"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(11)70266-6"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(03)00293-8"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2007.32"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2008.01671.x"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2009.01459.x"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181eee244"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2010.01833.x"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10194-012-0470-5"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3182a824f7"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0801384"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000197218.05284.82"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.167.18.1964"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2007.01360.x"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102412455708"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2008.01716.x"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000225052.35019.f9"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1186\/1129-2377-14-40"},{"key":"e_1_2_10_53_1","first-page":"9","article-title":"The International Classification of Headache Disorders","volume":"24","author":"Headache Classification Subcommittee of the International Headache Society","year":"2004","journal-title":"Cephalalgia"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-013-1388-7"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.41.2_Part_1.239"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1990.00530030091021"},{"key":"e_1_2_10_57_1","first-page":"31","article-title":"Idiopathic intracranial hypertension; incidence, presenting features and outcome in Northern Ireland 1991\u20101995","volume":"70","author":"Craig JJ","year":"2001","journal-title":"Ulster Med J"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-789X.2010.00799.x"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1988.00520320065016"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1097\/00041327-200103000-00004"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1988.00520320056015"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.1111\/ane.12060"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1993.00540010072020"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2011.03372.x"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1177\/112067210401400108"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.soard.2011.11.017"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2006.12.040"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181e0f838"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.45.9.1655"},{"key":"e_1_2_10_70_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2008.01240.x"},{"key":"e_1_2_10_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2009.06.030"},{"key":"e_1_2_10_72_1","doi-asserted-by":"publisher","DOI":"10.1097\/00041327-200106000-00014"},{"key":"e_1_2_10_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2009.11.001"}],"container-title":["Headache: The Journal of Head and Face Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fhead.12296","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/headachejournal.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/head.12296","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T09:59:32Z","timestamp":1762077572000},"score":1,"resource":{"primary":{"URL":"https:\/\/headachejournal.onlinelibrary.wiley.com\/doi\/10.1111\/head.12296"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2]]},"references-count":72,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["10.1111\/head.12296"],"URL":"https:\/\/doi.org\/10.1111\/head.12296","archive":["Portico"],"relation":{},"ISSN":["0017-8748","1526-4610"],"issn-type":[{"value":"0017-8748","type":"print"},{"value":"1526-4610","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,2]]}}}