{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T03:22:14Z","timestamp":1772508134470,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,4,17]],"date-time":"2014-04-17T00:00:00Z","timestamp":1397692800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Headache"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Headaches are commonly seen in those patients with human immunodeficiency virus (\n                      <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\n                      ) and are the most common form of pain reported among\n                      <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\n                      patients. There have been relatively few studies attempting to determine the rates and phenotypes of the headaches that occur in patients with\n                      <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>\n                      Patients with\n                      <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\n                      are susceptible to a much broader array of secondary headache causes, sometimes with atypical manifestations due to a dampened inflammatory response. The investigation of a headache in the\n                      <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\n                      patient should be thorough and focused on making sure that secondary and\n                      <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\n                      \u2010specific causes are either ruled out or treated if present.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      An effective treatment plan should incorporate the use of appropriate pharmacological agents along with the integration of non\u2010pharmacological therapies, such as relaxation and lifestyle regulation. When treating for headaches in patients with\n                      <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\n                      , it is important to keep in mind comorbidities and other medications, especially combination antiretroviral therapy. For those with complicated headache histories, referral to a specialized headache center may be appropriate.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/head.12357","type":"journal-article","created":{"date-parts":[[2014,4,18]],"date-time":"2014-04-18T00:43:29Z","timestamp":1397781809000},"page":"939-945","source":"Crossref","is-referenced-by-count":5,"title":["Clinical Aspects of Headache in\n                    <scp>HIV<\/scp>"],"prefix":"10.1111","volume":"54","author":[{"given":"Huma U.","family":"Sheikh","sequence":"first","affiliation":[{"name":"Department of Neurology, Harvard Medical School John Graham Headache Center Brigham and Women's Faulkner Hospital  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tracey A.","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Neurology Harvard Medical School Neurology\u2010Infectious Diseases Program Massachusetts General Hospital  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,4,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2011.02025.x"},{"key":"e_1_2_6_3_1","first-page":"1073","article-title":"HIV prevalence estimates \u2013 United States, 2006","volume":"57","author":"Centers for Disease Control and Prevention","year":"2008","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(99)00266-3"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.1999.3901003.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000117255"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-2982.2001.00186.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-857X(21)00093-4"},{"key":"e_1_2_6_9_1","first-page":"387","article-title":"Common neurologic complications of HIV\u20101 infection and AIDS","volume":"51","author":"Newton HB","year":"1995","journal-title":"Am Fam Physician"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.1995.hed3505245.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.47.2.487"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.1991.hed3108518.x"},{"key":"e_1_2_6_13_1","first-page":"1699","article-title":"Headache consortium releases guidelines for use of CT or MRI in migraine work up [Pract Guide]","volume":"62","author":"Morey SS","year":"2000","journal-title":"Am Fam Physician"},{"key":"e_1_2_6_14_1","first-page":"S550","article-title":"Clinical clues and clinical rules: Primary vs secondary headache","volume":"3","author":"Dodick DW","year":"2003","journal-title":"Adv StudMed"},{"key":"e_1_2_6_15_1","first-page":"685","article-title":"Evaluation of acute headache in adults","volume":"63","author":"Clinch CR","year":"2001","journal-title":"Am Fam Physician"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jana.2012.07.002"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa010399"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.trap.2012.11.003"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.55.6.754"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-2982.1997.1702067.x"},{"key":"e_1_2_6_21_1","unstructured":"New York State Department of Health AIDS Institute(2010).HIV Drug\u2010Drug Interactions. 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