{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:57:12Z","timestamp":1790211432481,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2014,6,4]],"date-time":"2014-06-04T00:00:00Z","timestamp":1401840000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Headache"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To describe the relationship between mood\/anxiety disorders and migraine headaches emphasizing the frequency of episodes based in a cross\u2010sectional analysis in the\n                      <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>\n                      razilian\n                      <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>\n                      ongitudinal\n                      <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>\n                      tudy of\n                      <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>\n                      dult\n                      <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>\n                      ealth.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>It has been suggested that frequency of migraine headaches can be directly associated with the presence of psychiatric disorders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Migraine headaches (\n                      <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>\n                      nternational\n                      <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>\n                      eadache\n                      <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>\n                      ociety criteria) was classified as &lt;1\u00d7\/month, 1\u00d7\/month\u20101\u00d7\/week, 2\u20106\u00d7\/week, and daily. Psychiatric disorders using the\n                      <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>\n                      linical\n                      <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>\n                      nterview\n                      <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>\n                      chedule \u2013\n                      <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>\n                      evised were classified in 6 categories: common mental (\n                      <jats:styled-content style=\"fixed-case\">CMD<\/jats:styled-content>\n                      ), major depressive (\n                      <jats:styled-content style=\"fixed-case\">MDD<\/jats:styled-content>\n                      ), generalized anxiety (\n                      <jats:styled-content style=\"fixed-case\">GAD<\/jats:styled-content>\n                      ), panic, obsessive\u2010compulsive (\n                      <jats:styled-content style=\"fixed-case\">OCD<\/jats:styled-content>\n                      ), and mixed anxiety and depressive (\n                      <jats:styled-content style=\"fixed-case\">MADD<\/jats:styled-content>\n                      ) disorders. We performed multivariate logistic models adjusted for age, race, education, marital status, income, and use of selective serotonin reuptake inhibitors.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In our sample, 1261 presented definite migraine and 10,531 without migraine headaches (reference). Our main result was an increase in the strength of association between migraine and\n                      <jats:styled-content style=\"fixed-case\">MDD<\/jats:styled-content>\n                      as frequency of migraine increased for all sample: odds ratio of 2.14 (95% confidence interval [\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      ] 1.33\u20103.43) for &lt;1 episode of migraine\/month to 6.94 (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      4.20\u201011.49) for daily headaches for all sample. Significant associations with migraine were also found for\n                      <jats:styled-content style=\"fixed-case\">GAD<\/jats:styled-content>\n                      ,\n                      <jats:styled-content style=\"fixed-case\">OCD<\/jats:styled-content>\n                      ,\n                      <jats:styled-content style=\"fixed-case\">MADD<\/jats:styled-content>\n                      , and\n                      <jats:styled-content style=\"fixed-case\">CMD<\/jats:styled-content>\n                      for total sample:\n                      <jats:styled-content style=\"fixed-case\">MDD<\/jats:styled-content>\n                      ,\n                      <jats:styled-content style=\"fixed-case\">GAD<\/jats:styled-content>\n                      ,\n                      <jats:styled-content style=\"fixed-case\">OCD<\/jats:styled-content>\n                      ,\n                      <jats:styled-content style=\"fixed-case\">MADD<\/jats:styled-content>\n                      , and\n                      <jats:styled-content style=\"fixed-case\">CMD<\/jats:styled-content>\n                      for women, and\n                      <jats:styled-content style=\"fixed-case\">MADD<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">CMD<\/jats:styled-content>\n                      for men. Among men with daily migraine complaint, we found a significant association between migraine and\n                      <jats:styled-content style=\"fixed-case\">OCD<\/jats:styled-content>\n                      after correction for multiple comparisons (odds ratio 29.86 [95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      4.66\u2010191.43]). Analyzing probable and definite migraine cases together, we replicated the findings in a lower magnitude.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The increase in migraine frequency was associated with progressively higher frequencies of having mood\/anxiety disorders in all samples suggesting for some psychiatric disorders a likely dose\u2010response effect especially for women.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/head.12397","type":"journal-article","created":{"date-parts":[[2014,6,4]],"date-time":"2014-06-04T09:12:58Z","timestamp":1401873178000},"page":"1310-1319","source":"Crossref","is-referenced-by-count":45,"title":["Migraine Headaches and Mood\/Anxiety Disorders in the\n                    <scp>ELSA B<\/scp>\n                    razil"],"prefix":"10.1111","volume":"54","author":[{"given":"Alessandra C.","family":"Goulart","sequence":"first","affiliation":[{"name":"Hospital Universit\u00e1rio Universidade de S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Itamar S.","family":"Santos","sequence":"additional","affiliation":[{"name":"Hospital Universit\u00e1rio Universidade de S\u00e3o Paulo  S\u00e3o Paulo Brazil"},{"name":"School of Medicine University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9 R.","family":"Brunoni","sequence":"additional","affiliation":[{"name":"Hospital Universit\u00e1rio Universidade de S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Ang\u00e9lica","family":"Nunes","sequence":"additional","affiliation":[{"name":"Federal University of Rio Grande do Sul  Porto Alegre Rio Grande do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9ria M.","family":"Passos","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais  Belo Horizonte Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosane H.","family":"Griep","sequence":"additional","affiliation":[{"name":"Laboratory of Health and Environment Education Oswaldo Cruz Institute Oswaldo Cruz Foundation  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo A.","family":"Lotufo","sequence":"additional","affiliation":[{"name":"Hospital Universit\u00e1rio Universidade de S\u00e3o Paulo  S\u00e3o Paulo Brazil"},{"name":"School of Medicine University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabela M.","family":"Bense\u00f1or","sequence":"additional","affiliation":[{"name":"Hospital Universit\u00e1rio Universidade de S\u00e3o Paulo  S\u00e3o Paulo Brazil"},{"name":"School of Medicine University of S\u00e3o Paulo  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