{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T18:32:31Z","timestamp":1791916351584,"version":"4.3.4"},"reference-count":19,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,2,13]],"date-time":"2015-02-13T00:00:00Z","timestamp":1423785600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Headache"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Family history of migraine is the most potent and consistent risk factor for migraine. However, there has been limited systematic research on the reliability of family history information in detecting migraine based on valid diagnostic interviews. This study systematically evaluated the accuracy of migraine defined by the\n                      <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>\n                      nternational\n                      <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>\n                      lassification of\n                      <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>\n                      eadache\n                      <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>\n                      isorders (\n                      <jats:styled-content style=\"fixed-case\">ICHD\u2010II<\/jats:styled-content>\n                      ) based on a direct structured interview compared to structured family history reports. The aim of the present study was to assess the validity of migraine diagnosis provided by family history compared with direct interview using a validated diagnostic interview of headache syndromes in the context of a family study of migraine comorbidity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The sample included 921 study participants identified in a cross\u2010sectional community\u2010based controlled family study of comorbidity of migraine and affective disorders recruited from the greater\n                      <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>\n                      ashington,\n                      <jats:styled-content style=\"fixed-case\">DC<\/jats:styled-content>\n                      community. Lifetime migraine and tension\u2010type headache were ascertained by direct clinical interview using a validated interview that collects\n                      <jats:styled-content style=\"fixed-case\">ICHD\u2010II<\/jats:styled-content>\n                      criteria for headache syndromes. A structured history of headache was also collected from all interviewed probands and relatives regarding their relatives. All family history reports were reviewed by the study neurologist according to\n                      <jats:styled-content style=\"fixed-case\">ICHD\u2010II<\/jats:styled-content>\n                      criteria. Family history ratings and diagnoses were made by the neurologist, who was blinded to the headache diagnosis obtained by direct interview.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The sensitivity and specificity of family history reports of migraine compared with direct interview were 38.6% and 96.8%, respectively, indicating that the false positive rate was very low, whereas the false negative rate was substantial. The positive and negative predictive values of migraine diagnosis provided by family member report are 90.0% and 67.6%, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our results confirm that migraine assessed by family member report largely underestimates migraine in relatives. This demonstrates the value of direct interviews with relatives rather than reliance on family history report in both clinical practice and family and genetic studies. Potential steps to improve the reliability of family history report in clinical settings are described.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/head.12501","type":"journal-article","created":{"date-parts":[[2015,2,13]],"date-time":"2015-02-13T08:45:20Z","timestamp":1423817120000},"page":"407-412","source":"Crossref","is-referenced-by-count":19,"title":["Accuracy of Family History Reports of Migraine in a Community\u2010Based Family Study of Migraine"],"prefix":"10.1111","volume":"55","author":[{"given":"Tarannum M.","family":"Lateef","sequence":"first","affiliation":[{"name":"Department of Neurology Children's National Medical Center George Washington University School of Medicine  Washington DC USA"},{"name":"Genetic Epidemiology Research Branch Intramural Research Program National Institutes of Health National Institute of Mental Health  Bethesda MD 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USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"Merikangas","sequence":"additional","affiliation":[{"name":"Genetic Epidemiology Research Branch Intramural Research Program National Institutes of Health National Institute of Mental Health  Bethesda MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,2,13]]},"reference":[{"issue":"1","key":"e_1_2_7_2_1","first-page":"9","article-title":"The international classification of headache disorders, 2nd edition","volume":"24","author":"Headache Classification Subcommittee of the International Headache 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