{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T03:56:26Z","timestamp":1763178986732,"version":"build-2065373602"},"reference-count":12,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,11,11]],"date-time":"2016-11-11T00:00:00Z","timestamp":1478822400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Headache"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:p>Hemicrania continua (HC) is a primary chronic headache disorder, characterized by a continuous and strictly unilateral headache, with possible cranial autonomic symptoms during episodes of pain exacerbation. The unilateral headache generally responds well to indomethacin; however, continuous indomethacin intake is often not tolerated due to severe adverse effects, like hypertension, gastrointestinal discomfort (especially if combined with aspirin), slightly increased risk of vascular events, and bronchial spasms. Therefore, alternative treatment options are desperately needed. Non\u2010invasive vagus nerve stimulation (nVNS) has been shown to be effective in patients with cluster headache, another trigeminal autonomic cephalalgia (TAC), with cranial parasympathetic autonomic activation during the attacks.<\/jats:p>","DOI":"10.1111\/head.12977","type":"journal-article","created":{"date-parts":[[2016,11,16]],"date-time":"2016-11-16T06:59:09Z","timestamp":1479279549000},"page":"298-301","source":"Crossref","is-referenced-by-count":15,"title":["Hemicrania Continua: Beneficial Effect of Non\u2010Invasive Vagus Nerve Stimulation in a Patient With a Contraindication for Indomethacin"],"prefix":"10.1111","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5299-388X","authenticated-orcid":false,"given":"Ozan","family":"Eren","sequence":"first","affiliation":[{"name":"Klinikum der Universit\u00e4t M\u00fcnchen \u2013 Neurologische Klinik und Poliklinik &amp; Deutsches Schwindel\u2010 und Gleichgewichtszentrum DSGZ Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Straube","sequence":"additional","affiliation":[{"name":"Klinikum der Universit\u00e4t M\u00fcnchen \u2013 Neurologische Klinik und Poliklinik &amp; Deutsches Schwindel\u2010 und Gleichgewichtszentrum DSGZ Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian","family":"Sch\u00f6berl","sequence":"additional","affiliation":[{"name":"Klinikum der Universit\u00e4t M\u00fcnchen \u2013 Neurologische Klinik und Poliklinik &amp; Deutsches Schwindel\u2010 und Gleichgewichtszentrum DSGZ Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Schankin","sequence":"additional","affiliation":[{"name":"Klinikum der Universit\u00e4t M\u00fcnchen \u2013 Neurologische Klinik und Poliklinik &amp; Deutsches Schwindel\u2010 und Gleichgewichtszentrum DSGZ Munich Germany"},{"name":"Department of Neurology University of Bern, Inselspital Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,11,11]]},"reference":[{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102413485658"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(08)70217-5"},{"key":"e_1_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1129-2377-15-S1-I8"},{"key":"e_1_2_2_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2007.01531.x"},{"key":"e_1_2_2_6_1","doi-asserted-by":"publisher","DOI":"10.1586\/14737175.7.12.1785"},{"key":"e_1_2_2_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-015-0543-3"},{"key":"e_1_2_2_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0b013e32832ae61e"},{"key":"e_1_2_2_9_1","first-page":"S104","article-title":"gammaCore (R) use for prevention and acute treatment of chronic cluster headache: Findings from the randomized phase of the PREVA Study","volume":"76","author":"Gaul C","year":"2014","journal-title":"Ann Neurol."},{"key":"e_1_2_2_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-2982.1984.0401065.x"},{"key":"e_1_2_2_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-010-0156-0"},{"key":"e_1_2_2_12_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0034-70942012000200004"},{"key":"e_1_2_2_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/1129-2377-14-S1-P230"}],"container-title":["Headache: The Journal of Head and Face Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fhead.12977","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/headachejournal.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/head.12977","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T10:40:08Z","timestamp":1762080008000},"score":1,"resource":{"primary":{"URL":"https:\/\/headachejournal.onlinelibrary.wiley.com\/doi\/10.1111\/head.12977"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,11]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["10.1111\/head.12977"],"URL":"https:\/\/doi.org\/10.1111\/head.12977","archive":["Portico"],"relation":{},"ISSN":["0017-8748","1526-4610"],"issn-type":[{"type":"print","value":"0017-8748"},{"type":"electronic","value":"1526-4610"}],"subject":[],"published":{"date-parts":[[2016,11,11]]}}}