{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T20:39:38Z","timestamp":1776803978323,"version":"3.51.2"},"reference-count":80,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,12,19]],"date-time":"2016-12-19T00:00:00Z","timestamp":1482105600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Headache"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The aims of this study were to investigate: (1) the prevalence and unadjusted and adjusted odds of 12\u2010month generalized anxiety disorder (GAD) among adults with migraine in comparison to those without migraine; (2) If debilitating pain and\/or limitations in instrumental activities of daily living (IADLs) are mediators of the migraine\u2010GAD association; and (3) Factors associated with past year GAD among adults with migraine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Secondary data analysis of the nationally representative 2012 Canadian Community Health Survey\u2010Mental Health (CCHS\u2010MS), a population\u2010based survey of community dwellers with a response rate of 68.9%. The first subsample included those with (n\u2009=\u20092232) and without migraine (n\u2009=\u200919,270), and the second subsample was restricted to those with migraine (n\u2009=\u20092232). GAD was based on the WHO\u2010CIDI scale.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Fully, 6% of those with migraines had past year GAD in comparison of 2.1% of those without migraine (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.001). The socio\u2010demographically adjusted odds of past year GAD were two and a half times higher among those with migraine than those without (OR= 2.46; 95% CI\u2009=\u20092.00, 3.02). A path analysis indicated that debilitating pain and limitations in IADLs were mediators in the relationship between migraine and GAD. In the sample restricted to migraineurs, the factors associated with higher odds of 12\u2010month GAD included having a university degree, having low income, being without a confidant, and being male.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Generalized anxiety disorder is robustly associated with migraine and targeted outreach and interventions are warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/head.13010","type":"journal-article","created":{"date-parts":[[2016,12,19]],"date-time":"2016-12-19T06:59:15Z","timestamp":1482130755000},"page":"375-390","source":"Crossref","is-referenced-by-count":28,"title":["Untangling the Association Between Migraine, Pain, and Anxiety: Examining Migraine and Generalized Anxiety Disorders in a Canadian Population Based Study"],"prefix":"10.1111","volume":"57","author":[{"given":"Esme","family":"Fuller\u2010Thomson","sequence":"first","affiliation":[{"name":"Factor\u2010Inwentash Faculty of Social Work University of Toronto Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janany","family":"Jayanthikumar","sequence":"additional","affiliation":[{"name":"Factor\u2010Inwentash Faculty of Social Work University of Toronto Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Senyo K.","family":"Agbeyaka","sequence":"additional","affiliation":[{"name":"Factor\u2010Inwentash Faculty of Social Work University of Toronto Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,12,19]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102413477736"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2001.041007646.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2006.00576.x"},{"key":"e_1_2_8_5_1","first-page":"23","article-title":"Migraine","volume":"12","author":"Gilmour H","year":"2001","journal-title":"Health Rep."},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102411425960"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.290.18.2443"},{"key":"e_1_2_8_8_1","first-page":"10","article-title":"Prevalence of migraine in the Canadian household population","volume":"25","author":"Ramage\u2010Morin PL","year":"2014","journal-title":"Health Rep."},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2011.01945.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102498018S2210"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-012-6725-x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2000.00148.x"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2012.12.006"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-008-0039-9"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.12004"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2005.09.010"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/da.10065"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/mpr.1359"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(93)90009-Q"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2004.446004.x"},{"key":"e_1_2_8_21_1","doi-asserted-by":"crossref","unstructured":"Fuller\u2010ThomsonE ShrummM BrennenstuhlS. 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