{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T14:28:26Z","timestamp":1792074506110,"version":"4.4.0"},"reference-count":57,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["headachejournal.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Headache"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:p>Dental pain is the most common acute pain presenting in the orofacial region; however, chronic pain conditions are also frequent and include; temporomandibular joint disorders (TMDs), primary headaches (neurovascular pain), painful post\u2010traumatic trigeminal neuropathy (PPTTN) and less commonly referred pain and idiopathic or centralized pain conditions. All of these conditions can mimic toothache and vice versa. Many of these conditions are comorbid with high levels of tension headache and migraine reported in patients with TMD; however, dentists remain unfamiliar with headaches and medics unfamiliar with toothache's multiple presentations. The anatomical complexity of the region, the potential exhaustive differential diagnoses and the multiple siloed training of specialties, leads to incorrect and delayed diagnosis and often results in patients undergoing inappropriate surgical and medical treatments. The continued inappropriate interventions may also complicate the later presentation of the patient with pain, by changing its phenotype, preventing a timely and correct diagnosis. Due to the variable presentation of toothache, which can mimic many different chronic pains including; episodic throbbing pain of migraine, the dull continuous pain of myofascial and arthrogenous TMDs or centralized facial pain, diagnosis can be complex. Neuralgic pain occurs in the dentition in health and with disease, mimicking conditions like PPTTN, trigeminal neuralgia (TN), and trigeminal autonomic cephalalgias (TACs), many patients are inappropriately diagnosed and treated, either by general medical practitioners assuming that the neuralgia is due to TN rather than more commonly presenting toothache or by a dentists or other surgeons continuing to treat TN or TACs with routine surgical care. Many patients are prescribed countless courses of antibiotics and undergo multiple surgical interventions simply as a result of poor education due to siloed specialty training. This must be addressed to improve patient safety.<\/jats:p>","DOI":"10.1111\/head.13689","type":"journal-article","created":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T09:53:40Z","timestamp":1572602020000},"page":"235-246","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":52,"title":["Tooth\u2010Related Pain or Not?"],"prefix":"10.1111","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2331-4005","authenticated-orcid":false,"given":"Tara","family":"Renton","sequence":"first","affiliation":[{"name":"Kings College Hospital\u2010Oral Surgery University of London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,11]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/PTS.0000000000000407"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.adaj.2016.04.015"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016357.2015.1042040"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.12968\/denu.2007.34.3.134"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102417704605"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI45178"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1067\/mem.2003.234"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1586\/ern.09.20"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2009.01436.x"},{"key":"e_1_2_12_11_1","doi-asserted-by":"crossref","unstructured":"International Headache Society (IHS).The International Classification of Headache Disorders. 3rd edn. (beta version) Headache Classification Committee of the International Headache Society (IHS) First Published June 14 2013. doi:10.1177\/0333102413485658.","DOI":"10.1177\/0333102413485658"},{"key":"e_1_2_12_12_1","unstructured":"International Craniofacial Disorders Classification (ICHD 3). Available at:https:\/\/www.ichd-3.org\/"},{"key":"e_1_2_12_13_1","unstructured":"American Association of Orofacial Pain (AAOP). Available at:http:\/\/www.aaop.org"},{"key":"e_1_2_12_14_1","unstructured":"American Association of Craniofacial pain (AACP). Available at:https:\/\/www.aacfp.org\/"},{"key":"e_1_2_12_15_1","unstructured":"International Association for the International Study of Pain (IASP).Classification of Chronic Pain. 2nd edn. (Revised). Available at:http:\/\/www.iasp-pain.org\/PublicationsNews\/Content.aspx?ItemNumber=1673"},{"key":"e_1_2_12_16_1","first-page":"99","article-title":"Canadian clinical practice guidelines for acute and chronic rhinosinusitis","volume":"40","author":"Desrosiers M","year":"2011","journal-title":"J Otolaryngol Head Neck Surg"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2006.00688.x"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2001.041007638.x"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.164.16.1769"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.CON.0000418648.54902.42"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(86)90213-7"},{"key":"e_1_2_12_22_1","first-page":"201","article-title":"Toothache of cardiac origin","volume":"13","author":"Kreiner M","year":"1999","journal-title":"J Orofac Pain"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.17636"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.69.810.300"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/671503"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2005.10.041"},{"key":"e_1_2_12_27_1","first-page":"52","article-title":"Pain preceding recurrent head and neck cancer","volume":"12","author":"Wong JK","year":"1998","journal-title":"J Orofac Pain"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.20141"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.11607\/jop.1151"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2000.0384"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2011.0137"},{"key":"e_1_2_12_32_1","first-page":"28","article-title":"Recognition and treatment of migraine patient in dental practice","volume":"75","author":"Weinberg MA","year":"2009","journal-title":"N Y State Dent J"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.23.1.23"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2005.05185.x"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2009.01899.x"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2007.01413.x"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coms.2007.12.008"},{"key":"e_1_2_12_38_1","first-page":"329","article-title":"Cracked tooth syndrome mimicking trigeminal autonomic cephalalgia: A report of four cases","volume":"48","author":"Noma N","year":"2017","journal-title":"Quintessence Int"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.4103\/aian.AIAN_348_17"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.13040"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-017-0629-5"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2011.06.017"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000000492"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102417706310"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2009.02.005"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2017.12.020"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-009-0329-y"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc16-2042"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0164994"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.54.0914"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.2016.444"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.1093\/med\/9780199236695.003.0007"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2017.09.009"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-017-0609-9"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.2007.01813.x"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.11607\/ofph.1746"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1111\/joor.12410"},{"key":"e_1_2_12_58_1","first-page":"2320","article-title":"Neurologist, otolaryngologist\u2026? Which specialist should treat facial pain?","volume":"95","author":"K\u00f6ling A","year":"1998","journal-title":"Lakartidningen"}],"container-title":["Headache: The Journal of Head and Face Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/head.13689","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/head.13689","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/headachejournal.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/head.13689","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T09:26:05Z","timestamp":1762075565000},"score":1,"resource":{"primary":{"URL":"https:\/\/headachejournal.onlinelibrary.wiley.com\/doi\/10.1111\/head.13689"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":57,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["10.1111\/head.13689"],"URL":"https:\/\/doi.org\/10.1111\/head.13689","archive":["Portico"],"relation":{},"ISSN":["0017-8748","1526-4610"],"issn-type":[{"value":"0017-8748","type":"print"},{"value":"1526-4610","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11]]},"assertion":[{"value":"2019-10-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}