{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T04:43:17Z","timestamp":1790397797313,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,5,5]],"date-time":"2020-05-05T00:00:00Z","timestamp":1588636800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008272","name":"Novartis Pharmaceuticals Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008272","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["headachejournal.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Headache"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Migraine is associated with debilitating symptoms that can affect daily functioning. \u201cMy Migraine Voice\u201d was a large, cross\u2010sectional, multi\u2010country online survey aimed at understanding disease burden directly from people with migraine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study reports on the social and economic impacts of migraine, specifically the impact on activities of daily living and the costs of migraine, from the point of view of people with migraine in the United States.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The online survey was administered to adults with a self\u2010reported diagnosis of migraine who experienced 4 or more monthly migraine days each month for the previous 3\u00a0months. Prespecified screening quotas were used so that 90% of respondents reported current or past use of preventive migraine medication, 80% of whom switched treatment (ie, changed their prescribed preventive medication at least once). The remaining 10% were preventive treatment na\u00efve (ie, never used any prescribed preventive medication). Burden of migraine on activities of daily living and caregivers (eg, functional limitations, fear of next migraine attack, sleep problems) and economic burden (eg, out\u2010of\u2010pocket costs, impact on work productivity using the validated work productivity and activity impairment questionnaire) reported by respondents from the United States are presented. Results are stratified by employment status, migraine frequency (chronic vs episodic migraine), and history of preventive treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thousand hundred and one individuals with migraine from the United States responded to the survey. Respondents reported limitations completing daily activities during all migraine phases, including during the premonitory\/aura and postdrome phases. Most (761\/1101 (69%)) relied on family, friends, or others for help with daily tasks and reported being helped a median of 9\u00a0days (25th percentile 5 days, 75th percentile 15 days) within the last 3 months. Respondents with chronic migraine reported being helped for more days (median 10 days, 25th percentile 5\u00a0days, 75th percentile 23 days) in the last 3 months. Almost all (962\/1101 (87%)) experienced sleep difficulties and 41% (448\/1101) (48% (336\/697) of those with 2 or more preventive treatment failures) were very or extremely fearful of a next migraine attack. Median (25th percentile, 75th percentile) monthly out\u2010of\u2010pocket costs of $90.00 ($30.00, $144.00) in doctor\u2019s fees (n\u00a0=\u00a0504), $124.00 ($60.00, $234.00) in health insurance (n\u00a0=\u00a0450), $40.00 ($20.00, $100.00) for prescriptions (n\u00a0=\u00a0630), and $50.00 ($0.00, $100.00) for complementary therapies (n\u00a0=\u00a0255) were reported. Those with 2 or more preventive treatment failures reported higher monthly out\u2010of\u2010pocket doctor fees (median $99.00 ($30.00, $150.00), n\u00a0=\u00a0388). Among employed respondents (n\u00a0=\u00a0661), migraine resulted in 22% absenteeism, 60% presenteeism, 65% work productivity loss, and 64% activity impairment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Migraine impacts individuals\u2019 activities of daily living, work\u2010life, and financial status, especially individuals with high needs, namely those with 4 or more monthly migraine days and prior treatment failures. People with migraine are impaired during all migraine phases, experience fear of their next migraine attack and sleep difficulties, and pay substantial monthly out\u2010of\u2010pocket costs for migraine. Burden is even greater among those who have had 2 or more preventive treatment failures. Impacts of migraine extend beyond probands to caregivers who help people with migraine with daily tasks, employers who are affected by employee absenteeism, presenteeism, and reduced productivity, and society which is burdened by lost and reduced economic productivity and healthcare costs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/head.13829","type":"journal-article","created":{"date-parts":[[2020,5,5]],"date-time":"2020-05-05T11:04:55Z","timestamp":1588676695000},"page":"1351-1364","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["United States Patients\u2019 Perspective of Living With Migraine: Country\u2010Specific Results From the Global \u201cMy Migraine Voice\u201d Survey"],"prefix":"10.1111","volume":"60","author":[{"given":"Sarah N.","family":"Gibbs","sequence":"first","affiliation":[{"name":"Partnership for Health Analytic Research (PHAR), LLC Beverly Hills CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shweta","family":"Shah","sequence":"additional","affiliation":[{"name":"Amgen, Inc. Thousand Oaks CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chinmay G.","family":"Deshpande","sequence":"additional","affiliation":[{"name":"Novartis Pharmaceuticals Corporation East Hanover NJ USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark E.","family":"Bensink","sequence":"additional","affiliation":[{"name":"Amgen, Inc. Thousand Oaks CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael S.","family":"Broder","sequence":"additional","affiliation":[{"name":"Partnership for Health Analytic Research (PHAR), LLC Beverly Hills CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula K.","family":"Dumas","sequence":"additional","affiliation":[{"name":"Migraine Again Irvine CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawn C.","family":"Buse","sequence":"additional","affiliation":[{"name":"Albert Einstein College of Medicine New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamela","family":"Vo","sequence":"additional","affiliation":[{"name":"Novartis Pharmaceuticals Corporation East Hanover NJ USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd J.","family":"Schwedt","sequence":"additional","affiliation":[{"name":"Mayo Clinic Phoenix AZ USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,5,5]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32154-2"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-018-0846-2"},{"key":"e_1_2_9_4_1","volume-title":"NHIS \u2010 Tables of Summary Health Statistics","year":"2018"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102410381145"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102414552532"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000252808.97649.21"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10194-012-0482-1"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102411398400"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102415580099"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2011.01945.x"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2016.10.005"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.12755"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(11)60562-4"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-018-0946-z"},{"issue":"1","key":"e_1_2_9_16_1","first-page":"319","article-title":"Burden and impact of migraine: A caregiver\u2019s perspective","volume":"37","author":"Ruiz de la Torre E","year":"2017","journal-title":"Int Headache Congr"},{"issue":"1","key":"e_1_2_9_17_1","first-page":"319","article-title":"Real\u2010world patient perspective on the burden and impact of migraine","volume":"37","author":"Ruiz de la Torre E","year":"2017","journal-title":"Int Headache Congr"},{"key":"e_1_2_9_18_1","volume-title":"Human Subject Regulations Decision Charts","author":"US Department of Health and Human Services"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.2165\/00019053-199304050-00006"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-011-0233-z"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.2165\/11530030-000000000-00000"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-017-0641-9"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.13435"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.13254"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2016.02.013"},{"key":"e_1_2_9_26_1","volume-title":"Out\u2010of\u2010Pocket Spending"},{"key":"e_1_2_9_27_1","volume-title":"Medicare Beneficiaries\u2019 Out\u2010of\u2010Pocket Health Care Spending as a Share of Income Now and Projections for the Future","author":"Cubanski J","year":"2018"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2015.07.013"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-018-0907-6"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g1416"},{"key":"e_1_2_9_31_1","volume-title":"National Population by Characteristics: 2010\u20102017","author":"US Census Bureau","year":"2018"},{"key":"e_1_2_9_32_1","volume-title":"Average Hourly and Weekly Earnings of All Employees on Private Nonfarm Payrolls by Industry Sector, Seasonally Adjusted","author":"Table B\u20103"},{"key":"e_1_2_9_33_1","first-page":"65","article-title":"Consumers\u2019 knowledge about their health insurance coverage","volume":"5","author":"Marquis MS","year":"1983","journal-title":"Health Care Financ Rev"}],"container-title":["Headache: The Journal of Head and Face Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fhead.13829","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/head.13829","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/head.13829","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/headachejournal.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/head.13829","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T11:26:03Z","timestamp":1762082763000},"score":1,"resource":{"primary":{"URL":"https:\/\/headachejournal.onlinelibrary.wiley.com\/doi\/10.1111\/head.13829"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,5]]},"references-count":32,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["10.1111\/head.13829"],"URL":"https:\/\/doi.org\/10.1111\/head.13829","archive":["Portico"],"relation":{},"ISSN":["0017-8748","1526-4610"],"issn-type":[{"value":"0017-8748","type":"print"},{"value":"1526-4610","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,5]]},"assertion":[{"value":"2019-09-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}