{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T01:53:02Z","timestamp":1791942782083,"version":"4.3.4"},"reference-count":15,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,8,17]],"date-time":"2020-08-17T00:00:00Z","timestamp":1597622400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["headachejournal.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Headache"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:p>Headache was reported in up to one\u2010third of the hospitalized patients; yet, the clinical characteristics of headache associated with coronavirus disease 2019 (COVID\u201019) have not been defined. This observational case study included patients who were consulted to headache unit due to headache and had COVID\u201019 illness. Headache features in 13 PCR\u2010confirmed COVID\u201019 patients with mild symptoms were reported. Headache was the isolated symptom of the COVID\u201019 in 3 patients and emerged as an early symptom during the disease course in all patients. Patients specified severe, rapid onset, unrelenting headache with migraine\u2010like features, as well as unusual sensory symptoms such as anosmia, and gastrointestinal symptoms such as diarrhea and loss of appetite and weight. Headache lasted up to 3\u00a0days in 70% of the patients and resolved in all patients within 2\u00a0weeks. Despite the fact that most of the patients were female and headache characteristics were suggestive of migraine, majority of patients were not suffering from primary headaches. It was concluded that headache could be an isolated symptom of COVID\u201019, which might possibly be ignored in asymptomatic patients. Headaches associated with COVID\u201019 included features resembling migraine and\/or atypical symptoms including anosmia and diarrhea.<\/jats:p>","DOI":"10.1111\/head.13940","type":"journal-article","created":{"date-parts":[[2020,8,13]],"date-time":"2020-08-13T15:34:38Z","timestamp":1597332878000},"page":"1788-1792","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":58,"title":["Case Series of Headache Characteristics in COVID\u201019: Headache Can Be an Isolated Symptom"],"prefix":"10.1111","volume":"60","author":[{"given":"Tu\u011f\u00e7e","family":"Toptan","sequence":"first","affiliation":[{"name":"Department of Neurology &amp; Algology Gazi University Hospital Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c7ile","family":"Aktan","sequence":"additional","affiliation":[{"name":"Department of Neurology &amp; Algology Gazi University Hospital Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet","family":"Ba\u015far\u0131","sequence":"additional","affiliation":[{"name":"Department of Neurology &amp; Algology Gazi University Hospital Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hayrunnisa","family":"Bolay","sequence":"additional","affiliation":[{"name":"Department of Neurology &amp; Algology Gazi University Hospital Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,8,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2020.1127"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2002032"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.13856"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.02.052"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2020.02.018"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30183-5"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30211-7"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2020-320926"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2020.25.16.2000508"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102417738202"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.13853"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2020.2065"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1101\/2020.03.25.009084"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1101\/2020.03.31.013268"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2020.2125"}],"container-title":["Headache: The Journal of Head and Face Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fhead.13940","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/head.13940","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/head.13940","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/headachejournal.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/head.13940","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T08:26:42Z","timestamp":1762072002000},"score":1,"resource":{"primary":{"URL":"https:\/\/headachejournal.onlinelibrary.wiley.com\/doi\/10.1111\/head.13940"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,17]]},"references-count":15,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["10.1111\/head.13940"],"URL":"https:\/\/doi.org\/10.1111\/head.13940","archive":["Portico"],"relation":{},"ISSN":["0017-8748","1526-4610"],"issn-type":[{"value":"0017-8748","type":"print"},{"value":"1526-4610","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,17]]},"assertion":[{"value":"2020-06-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}