{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T19:45:59Z","timestamp":1765827959551,"version":"build-2065373602"},"reference-count":55,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,9,30]],"date-time":"2020-09-30T00:00:00Z","timestamp":1601424000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008651","name":"Express Scripts","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008651","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["headachejournal.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Headache"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To identify meaningful migraine outcome measures among key stakeholders to inform value\u2010based contracts for migraine medications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Value\u2010based contracts linking medication payments to predefined performance metrics aim to promote value through aligned incentives and shared risk between manufacturers and payers. The emergence of new and expensive pharmaceuticals for migraine presents an opportunity for value\u2010based contract development. However, uncertainty remains around which outcomes are most meaningful to all migraine stakeholders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study utilized a Delphi survey to incorporate views from 82 stakeholders, including patients (n\u00a0=\u00a021), providers (n\u00a0=\u00a023), payers (n\u00a0=\u00a010), employers (n\u00a0=\u00a018), and pharmaceutical company representatives (n\u00a0=\u00a010). A list of 15 migraine\u2010related outcomes was created from a literature review and subject matter expert consultation. Stakeholders reported on the value of these outcomes through a 5\u2010point Likert scale and selection of their top 3 most meaningful outcomes. All participants except patients and employers also used a 5\u2010point Likert scale to rate the feasibility of collecting each outcome measure. Consensus was defined as \u226575% agreement on the importance and feasibility of an outcome (Likert scores \u22654\/5 or selection of an outcome as most meaningful).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After 2 rounds, consensus was achieved for importance of 9 outcomes on the Likert scale. \u201cDecrease in migraine frequency\u201d reached 100% agreement (82\/82), followed by \u201cincreased ability to resume normal activities\u201d (96%, 79\/82). When asked to choose the 3 most meaningful outcomes, stakeholders selected \u201cdecrease in migraine frequency\u201d (88%, 72\/82) followed by \u201cdecrease in migraine severity\u201d (80%, 66\/82). The 2 measures rated as most feasibly collected were \u201cdecrease in emergency department\/urgent care visits\u201d (95%, 40\/42) and \u201cdecrease in migraine frequency\u201d (90%, 38\/42). There were statistically significant differences between non\u2010patient and patient stakeholders in selection of \u201cdecrease in emergency department\/urgent care visits\u201d [20% (12\/61) vs 0% (0\/21),\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.031]; and employer and patient stakeholders in selection of \u201cdecrease in work days missed\u201d [44% (8\/18) vs 5% (1\/21),\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.006] and \u201cdecrease in emergency department\/urgent care visits\u201d [22% (4\/18) vs 0% (0\/21),\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.037] as most meaningful outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The measures \u201cdecrease in migraine frequency\u201d followed by \u201cdecrease in migraine severity\u201d were identified as top priority migraine outcome measures.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/head.13978","type":"journal-article","created":{"date-parts":[[2020,9,30]],"date-time":"2020-09-30T16:05:11Z","timestamp":1601481911000},"page":"2139-2151","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Identifying Outcome Measures for Migraine Value\u2010Based Contracting Using the Delphi Method"],"prefix":"10.1111","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8938-4236","authenticated-orcid":false,"given":"Elizabeth C. 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