{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T11:19:36Z","timestamp":1767093576541,"version":"build-2065373602"},"reference-count":28,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,10,12]],"date-time":"2020-10-12T00:00:00Z","timestamp":1602460800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["headachejournal.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Headache"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objective\/Background<\/jats:title>\n                    <jats:p>This study aimed to clarify the relationship between migraine\u2010like headache and ventriculo\u2010arterial coupling after transcatheter closure of the atrial septal defect in children. We hypothesized that migraine headache after defect closure would be related to an abnormal hemodynamic response against an increased left ventricular filling.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>A retrospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We calculated the end\u2010ventricular systolic elastance (Ees), effective arterial elastance (Ea), and ventricular energy efficiency approximated based on echocardiography before and after defect closure, and compared these parameters between the subjects with and without headache after defect closure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 167 subjects were studied. Age at the procedure, defect diameter, and pulmonary to systemic blood flow ratio were 11 (9\u201017) years, 12.8 (9.2\u201016.0) mm, and 1.8 (1.6\u20102.3), respectively. We identified 47 (28%) subjects with migraine headache after defect closure. Although there was no significant difference in the Ees, Ea, and ventricular energy efficiency before defect closure between the groups, the Ees (4.0 [3.4\u20104.9] vs 4.8 [3.7\u20106.1],\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.014) and ventricular energy efficiency (0.79 [0.76\u20100.82] vs 0.83 [0.79\u20100.85],\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.001) after defect closure in subjects with headache were significantly lower than those in subjects without headache. Migraine headache after defect closure was significantly associated with age (odds ratio: 0.97, 95% confidential interval: 0.94\u20101.00,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.036) and a decrease in the ventricular energy efficiency after defect closure (odds ratio: 6.42, 95% confidential interval: 2.76\u201014.90,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A loss of ventricular energy efficiency was common in pediatric subjects with migraine\u2010like headache after transcatheter closure of the atrial septal defect, which suggested that the left ventricular function maladaptation was related to headache development after defect closure. We advocate that an impaired ventriculo\u2010arterial coupling may be one of the mechanisms for developing attacks in not only this population but also in other patients with migraine.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/head.13990","type":"journal-article","created":{"date-parts":[[2020,10,12]],"date-time":"2020-10-12T16:40:10Z","timestamp":1602520810000},"page":"2421-2430","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Headache and Left Ventricular Efficiency After Transcatheter Closure of Atrial Septal Defect"],"prefix":"10.1111","volume":"60","author":[{"given":"Ryohei","family":"Matsuoka","sequence":"first","affiliation":[{"name":"Department of Pediatrics Japan Community Healthcare Organization Kyusyu Hospital Kitakyusyu 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Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Ezaki","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Japan Community Healthcare Organization Kyusyu Hospital Kitakyusyu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirohito","family":"Doi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Japan Community Healthcare Organization Kyusyu Hospital Kitakyusyu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mamie","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Japan Community Healthcare Organization Kyusyu Hospital Kitakyusyu 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