{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T22:55:37Z","timestamp":1790636137026,"version":"4.1.0"},"reference-count":54,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,11,16]],"date-time":"2020-11-16T00:00:00Z","timestamp":1605484800000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008460","name":"National Center for Complementary and Integrative Health","doi-asserted-by":"publisher","award":["K23AT009706"],"award-info":[{"award-number":["K23AT009706"]}],"id":[{"id":"10.13039\/100008460","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000862","name":"Doris Duke Charitable Foundation","doi-asserted-by":"publisher","award":["Fellowship to Retain Clinical Scientists"],"award-info":[{"award-number":["Fellowship to Retain Clinical Scientists"]}],"id":[{"id":"10.13039\/100000862","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["headachejournal.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Headache"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Scalable, accessible forms of behavioral therapy for migraine prevention are needed. We assessed the feasibility and acceptability of progressive muscle relaxation (PMR) delivered by a smartphone application (app) in the Primary Care setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This pilot study was a non\u2010blinded, randomized, parallel\u2010arm controlled trial of adults with migraine and 4+ headache days\/month. Eligible participants spoke English and owned a smartphone. All participants were given the RELAXaHEAD app which includes an electronic headache diary. Participants were randomized to receive 1 of the 2 versions of the app\u2010one with PMR and the other without PMR. The primary outcomes were measures of feasibility (adherence to the intervention and diary entries during the 90\u2010day interval) and acceptability (satisfaction levels). We conducted exploratory analyses to determine whether there was a\u00a0change\u00a0in Migraine Disability Assessment Scale (MIDAS) scores or a change\u00a0in headache days.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 139 participants (77 PMR, 62 control), 116 (83%) were female, mean age was 41.7\u00a0\u00b1\u00a012.8 years. Most patients 108\/139 (78%) had moderate\u2010severe disability. Using a 1\u20105 Likert scale, participants found the app easy to use (mean 4.2\u00a0\u00b1\u00a00.7) and stated that they would be happy to engage in the PMR intervention again (mean 4.3\u00a0\u00b1\u00a00.6). For the first 6\u00a0weeks, participants practiced PMR 2\u20104\u00a0days\/week. Mean per session duration was 11.1\u00a0\u00b1\u00a08.3\u00a0minutes. Relative to the diary\u2010only group, the PMR group showed a greater non\u2010significant decline in mean MIDAS scores (\u22128.7 vs \u221222.7,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.100) corresponding to a small\u2010moderate mean effect size (Cohen\u2019s\n                      <jats:italic>d<\/jats:italic>\n                      \u00a0=\u00a00.38).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Smartphone\u2010delivered PMR may be an acceptable, accessible form of therapy for migraine. Mean effects show a small\u2010moderate mean effect size in disability scores.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/head.14010","type":"journal-article","created":{"date-parts":[[2020,11,17]],"date-time":"2020-11-17T02:12:13Z","timestamp":1605579133000},"page":"2232-2246","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":55,"title":["Smartphone\u2010Delivered Progressive Muscle Relaxation for the Treatment of Migraine in Primary Care: A Randomized Controlled Trial"],"prefix":"10.1111","volume":"60","author":[{"given":"Mia T.","family":"Minen","sequence":"first","affiliation":[{"name":"Department of Neurology NYU Langone Health New York NY USA"},{"name":"Department of Population Health NYU Langone Health New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samrachana","family":"Adhikari","sequence":"additional","affiliation":[{"name":"Department of Population Health NYU Langone Health New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane","family":"Padikkala","sequence":"additional","affiliation":[{"name":"Center for Healthcare Innovation and Delivery Science NYU Langone Health New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumaiya","family":"Tasneem","sequence":"additional","affiliation":[{"name":"Center for Healthcare Innovation and Delivery Science NYU Langone Health New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley","family":"Bagheri","sequence":"additional","affiliation":[{"name":"Center for Healthcare Innovation and Delivery Science NYU Langone Health New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Goldberg","sequence":"additional","affiliation":[{"name":"Department of Medicine Faculty Group Practices NYU Langone Health New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Powers","sequence":"additional","affiliation":[{"name":"Behavioral Medicine Headache Medicine Clinical Psychology Cincinnati Children's Hospital Cincinnati OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard B.","family":"Lipton","sequence":"additional","affiliation":[{"name":"Montefiore Headache Center Department of Neurology Albert Einstein College of Medicine New York NY USA"},{"name":"Montefiore Headache Center Department of Population Health Albert Einstein College of Medicine New York NY USA"},{"name":"Montefiore Headache Center Department of Psychiatry and Behavioral Sciences Albert Einstein College of Medicine New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,11,16]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.12482"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/2049463712459691"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c4871"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.282533"},{"key":"e_1_2_8_6_1","volume-title":"Evidence\u2010Based Guidelines for Migraine Headache: Behavioral and Physical Treatments","author":"Campbell J","year":"2000"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.12774"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2012.02265.x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.13588"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102415593086"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.12803"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102413490343"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.12605"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-012-1073-2"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/pm\/pny028"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.13738"},{"key":"e_1_2_8_17_1","unstructured":"Available at:irody.com. 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