{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T11:56:04Z","timestamp":1762084564679,"version":"build-2065373602"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,12,30]],"date-time":"2020-12-30T00:00:00Z","timestamp":1609286400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["headachejournal.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Headache"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study compared migraine medication prescribing between patients with a migraine diagnosis who used versus did not use the emergency department (ED) for migraine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Headache is the fifth most common chief complaint for ED visits nationwide and the third most common potentially avoidable ED diagnosis in the University of Colorado Health system. The reasons some patients use the ED for migraine management while others do not and whether some ED admissions might be preventable remain unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective cohort study identified adults with migraine\u2010related diagnoses within 1\u00a0year before the index date of July 1, 2018 and compared patient characteristics and migraine medication prescribing patterns between those who did or did not have a subsequent migraine\u2010related ED encounter the following year. ED admission notes were manually reviewed to identify potentially preventable circumstances that led to the ED visit. The primary outcome was the proportion of patients with an active triptan prescription at the index date.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 3843 patients identified, 35 patients (0.9%) had a migraine\u2010related ED encounter. Of these, 17\/35 (49%) had an active triptan prescription compared to 1360\/3808 (36%) of non\u2010ED utilizers (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.114), OR 1.22 (95% CI 0.61\u20132.45). More ED utilizers had an active prescription for opioids (11\/35 [31%] vs. 663\/3808 [17%],\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.030) and migraine preventive therapy (19\/35 [54%] vs. 1149\/3808 [30%],\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.002), and neurology referrals (20\/35 [57%] vs. 654\/3808 [17%],\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001) compared to non\u2010ED utilizers. The most common circumstance for migraine\u2010related ED visits was nonresponse to migraine abortive medications administered at home.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Triptan prescribing did not differ between ED utilizers and non\u2010ED utilizers for migraine. Overall, less than half of the total patient population had a triptan prescribed. More ED utilizers had neurology referrals, prescriptions for opioids and preventive therapies, and a history of previous ED visit for any reason, which may be markers for higher disease severity or behavior patterns. Future research and interventions to reduce migraine\u2010related ED use could target high\u2010risk patients such as those with previous ED visits for any indication and neurology referrals.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/head.14029","type":"journal-article","created":{"date-parts":[[2020,12,30]],"date-time":"2020-12-30T16:30:30Z","timestamp":1609345830000},"page":"455-461","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Prescribing practices of migraine\u2010specific pharmacotherapy associated with emergency department use for migraine"],"prefix":"10.1111","volume":"61","author":[{"given":"Vivian","family":"Cheng","sequence":"first","affiliation":[{"name":"Department of Clinical Pharmacy University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences Aurora CO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah J.","family":"Billups","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences Aurora CO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph J.","family":"Saseen","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences Aurora CO USA"},{"name":"Department of Family Medicine University of Colorado School of Medicine Aurora CO 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