{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T16:08:17Z","timestamp":1790611697517,"version":"4.1.0"},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["headachejournal.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Headache"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Reversible cerebral vasoconstriction syndrome (RCVS) and transient global amnesia (TGA) are acute and self\u2010limiting intra\u2010cerebral conditions. Although previously studied as independent phenomena, there are increasing reports of co\u2010occurrence of these two pathologies. We report a 55\u2010year\u2010old male who presented to the hospital with recurrent thunderclap headaches over the course of 1\u2009week with sudden onset of anterograde memory loss. His medications included a selective serotonin reuptake inhibitor and intermittent use of pseudoephedrine. On examination he was amnestic to recent events and notably perseverating. Magnetic resonance imaging of the brain without contrast showed a small, punctate focus of restricted diffusion in the left hippocampus. He was diagnosed with TGA based on his clinical presentation. His headaches and amnesia resolved over the next 12\u2009h throughout the course of his stay with acetaminophen and oral verapamil and he was discharged. Repeat computed tomography angiogram at 2\u2009weeks revealed diffuse and segmental narrowing of the anterior and posterior intracranial circulation, which resolved on follow\u2010up imaging at 3\u2009months, confirming RCVS. The acute and reversible nature of these conditions and increasing reports of co\u2010occurrence suggests a common pathophysiologic link. We review the literature highlighting similar cases and the presumed pathophysiology.<\/jats:p>","DOI":"10.1111\/head.14432","type":"journal-article","created":{"date-parts":[[2023,1,2]],"date-time":"2023-01-02T02:38:19Z","timestamp":1672627099000},"page":"168-172","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The link between reversible cerebral vasoconstriction syndrome and transient global amnesia"],"prefix":"10.1111","volume":"63","author":[{"given":"Rahul","family":"Chandra","sequence":"first","affiliation":[{"name":"Neurology Cleveland Clinic Foundation  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3840-1526","authenticated-orcid":false,"given":"Harneel Singh","family":"Saini","sequence":"additional","affiliation":[{"name":"Neurology Allegheny General Hospital  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaitlyn N.","family":"Palmer","sequence":"additional","affiliation":[{"name":"Neurology Cleveland Clinic Foundation  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Russell","family":"Cerejo","sequence":"additional","affiliation":[{"name":"Neurology Allegheny General Hospital  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,1]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-019-09594-5"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000012223"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.56.7460"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.53.10.834"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000006917"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-019-09495-7"},{"issue":"15","key":"e_1_2_5_8_1","first-page":"94","article-title":"Simultaneous subarachnoid hemorrhage and transient global amnesia secondary to reversible cerebral vasoconstriction syndrome (2876)","volume":"94","author":"Beer R","year":"2020","journal-title":"Neurology"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.24652"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000130504.88404.C9"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2020.00034"}],"container-title":["Headache: The Journal of Head and Face Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/head.14432","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/head.14432","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/headachejournal.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/head.14432","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T11:00:04Z","timestamp":1762081204000},"score":1,"resource":{"primary":{"URL":"https:\/\/headachejournal.onlinelibrary.wiley.com\/doi\/10.1111\/head.14432"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["10.1111\/head.14432"],"URL":"https:\/\/doi.org\/10.1111\/head.14432","archive":["Portico"],"relation":{},"ISSN":["0017-8748","1526-4610"],"issn-type":[{"value":"0017-8748","type":"print"},{"value":"1526-4610","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"2022-07-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-01","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}