{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:51:09Z","timestamp":1787014269908,"version":"build-2736575974"},"reference-count":36,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T00:00:00Z","timestamp":1705536000000},"content-version":"am","delay-in-days":382,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#am"},{"start":{"date-parts":[[2023,1,18]],"date-time":"2023-01-18T00:00:00Z","timestamp":1674000000000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["1R61NS113315\u201001"],"award-info":[{"award-number":["1R61NS113315\u201001"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000005","name":"U.S. Department of Defense","doi-asserted-by":"publisher","award":["W81XWH\u201019\u20100534"],"award-info":[{"award-number":["W81XWH\u201019\u20100534"]}],"id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["headachejournal.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Headache"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives\/Background<\/jats:title>\n                    <jats:p>Post\u2010traumatic headache (PTH) is a common symptom after mild traumatic brain injury (mTBI). Although there have been several studies that have used clinical features of PTH to attempt to predict headache recovery, currently no accurate methods exist for predicting individuals\u2019 improvement from acute PTH. This study investigated the utility of clinical questionnaires for predicting (i) headache improvement at 3 and 6\u2009months, and (ii) headache trajectories over the first 3\u2009months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a clinic\u2010based observational longitudinal study of patients with acute PTH who completed a battery of clinical questionnaires within 0\u201359\u2009days post\u2010mTBI. The battery included headache history, symptom evaluation, cognitive tests, psychological tests, and scales assessing photosensitivity, hyperacusis, insomnia, cutaneous allodynia, and substance use. Each participant completed a web\u2010based headache diary, which was used to determine headache improvement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirty\u2010seven participants with acute PTH (mean age\u00a0=\u00a042.7, standard deviation [SD]\u00a0=\u00a012.0; 25 females\/12 males) completed questionnaires at an average of 21.7 (SD\u00a0=\u00a013.1) days post\u2010mTBI. The classification of headache improvement or non\u2010improvement at 3 and 6\u2009months achieved cross\u2010validation area under the curve (AUC) of 0.72 (95% confidence interval [CI] 0.55 to 0.89) and 0.84 (95% CI 0.66 to 1.00). Sub\u2010models trained using only the top five features still achieved 0.72 (95% CI 0.55 to 0.90) and 0.77 (95% CI 0.52 to 1.00) AUC. The top five contributing features were from three questionnaires: Pain Catastrophizing Scale total score and helplessness sub\u2010domain score; Sports Concussion Assessment Tool Symptom Evaluation total score and number of symptoms; and the State\u2010Trait Anxiety Inventory score. The functional regression model achieved  for modeling headache trajectory over the first 3\u2009months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Questionnaires completed following mTBI have good utility for predicting headache improvement at 3\u2009and 6\u2009months in the future as well as the evolving headache trajectory. Reducing the battery to only three questionnaires, which assess post\u2010concussive symptom load and biopsychosocialecologic factors, was helpful to determine a reasonable prediction accuracy for headache improvement.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/head.14450","type":"journal-article","created":{"date-parts":[[2023,1,18]],"date-time":"2023-01-18T07:20:41Z","timestamp":1674026441000},"page":"136-145","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Developing multivariable models for predicting headache improvement in patients with acute post\u2010traumatic headache attributed to mild traumatic brain injury: A preliminary study"],"prefix":"10.1111","volume":"63","author":[{"given":"Lingchao","family":"Mao","sequence":"first","affiliation":[{"name":"School of Industrial and Systems Engineering Georgia Tech  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gina","family":"Dumkrieger","sequence":"additional","affiliation":[{"name":"Department of Neurology Mayo Clinic  Phoenix Arizona USA"},{"name":"School of Computing and Augmented Intelligence Arizona State University  Tempe Arizona USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dohyun","family":"Ku","sequence":"additional","affiliation":[{"name":"School of Industrial and Systems Engineering Georgia Tech  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Ross","sequence":"additional","affiliation":[{"name":"Phoenix VA Health Care System  Phoenix Arizona USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Visar","family":"Berisha","sequence":"additional","affiliation":[{"name":"ASU\u2010Mayo Center for Innovative Imaging  Phoenix Arizona USA"},{"name":"School of Electrical, Computer and Energy Engineering and College of Health Solutions Arizona State University  Tempe Arizona USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd J.","family":"Schwedt","sequence":"additional","affiliation":[{"name":"Department of Neurology Mayo Clinic  Phoenix Arizona USA"},{"name":"ASU\u2010Mayo Center for Innovative Imaging  Phoenix Arizona USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[{"name":"School of Industrial and Systems Engineering Georgia Tech  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9035-8748","authenticated-orcid":false,"given":"Catherine D.","family":"Chong","sequence":"additional","affiliation":[{"name":"Department of Neurology Mayo Clinic  Phoenix Arizona USA"},{"name":"ASU\u2010Mayo Center for Innovative Imaging  Phoenix Arizona USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,1,18]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-022-01398-9"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/emermed-2015-205429"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4637.2007.00404.x"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2011.1914"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-018-0838-2"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-020-1080-2"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-021-01296-6"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102417738202"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.HTR.0000300227.67748.77"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.2009.059832"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1389-9457(00)00065-4"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000067570"},{"issue":"2","key":"e_1_2_12_14_1","first-page":"108","article-title":"Photosensitivity and panic\u2010agoraphobic spectrum: a pilot study","volume":"48","author":"Bossini L","year":"2013","journal-title":"Riv Psichiatr"},{"key":"e_1_2_12_15_1","first-page":"167","article-title":"Sensibilit\u00e0 alla luce e psicopatologia: validazione del Questionario per la Valutazione della Fotosensibilit\u00e0 (QVF)","volume":"51","author":"Bossini L","year":"2006","journal-title":"Med Psicosomatica"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1025570508954"},{"key":"e_1_2_12_17_1","volume-title":"Manual for the State\u2010Trait Anxiety Inventory","author":"Spielberger CD","year":"1983"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1207\/s15327752jpa6703_13"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546516648141"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-016-3703-5"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-84858-7"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1109\/LSP.2014.2337313"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.2307\/2531595"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-statistics-010814-020413"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/10618600.2014.901914"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1201\/9781420010404"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmrj.2010.06.013"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000001342"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0000000000000749"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1037\/hea0000877"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002508-200106000-00009"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40279-019-01240-4"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1080\/13803395.2015.1004303"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-020-01103-8"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.12726"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2018.6328"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.1312"}],"container-title":["Headache: The Journal of Head and Face Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/head.14450","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/head.14450","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/headachejournal.onlinelibrary.wiley.com\/doi\/am-pdf\/10.1111\/head.14450","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/headachejournal.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/head.14450","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T11:00:20Z","timestamp":1762081220000},"score":1,"resource":{"primary":{"URL":"https:\/\/headachejournal.onlinelibrary.wiley.com\/doi\/10.1111\/head.14450"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["10.1111\/head.14450"],"URL":"https:\/\/doi.org\/10.1111\/head.14450","archive":["Portico"],"relation":{},"ISSN":["0017-8748","1526-4610"],"issn-type":[{"value":"0017-8748","type":"print"},{"value":"1526-4610","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"2022-05-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}