{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T10:37:32Z","timestamp":1762079852817,"version":"build-2065373602"},"reference-count":44,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T00:00:00Z","timestamp":1675814400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["K23 NS048288","K23NS096107"],"award-info":[{"award-number":["K23 NS048288","K23NS096107"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["headachejournal.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Headache"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>In this secondary analysis of mobile health headache diary data, we evaluated the relationship between adherence to medication used for the acute treatment of migraine and lifetime history of an anxiety or depression disorder.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Medication non\u2010adherence can produce poor clinical efficacy and may be associated with medication overuse. Medication overuse was defined by taking a migraine\u2010specific medication (MSM) for \u226510\u2009days\/month, an opioid or barbiturate for \u226510\u2009days\/month, or a nonsteroidal anti\u2010inflammatory drug for \u226515\u2009days\/month and having \u226515\u2009headache days\/month. Extant literature predominantly evaluates fixed\u2010schedule medication adherence. Little is known about predictors of adherence to as\u2010needed medication such as those used for the acute treatment of migraine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Adults with prior migraine diagnosis and at least 4\u2009headache days\/month completed baseline questionnaires assessing lifetime history of depression or anxiety disorder diagnoses and were asked to record 90\u2009days of once\u2010daily electronic headache diaries soliciting: Headache occurrence; symptoms; medication taken, if any, for the acute treatment of migraine; and their pain level (mild, moderate, severe) when the medication was taken. The 193 participants who completed \u226530\u2009days of headache diary were included in this secondary analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A MSM was used as the first medication taken on 45.7% (2825\/6176) of headache days. Nearly a quarter of the sample (45\/193, 23.3%) overused medications for acute treatment of migraine. Medication overuse was more common in patients with a history of an anxiety disorder, odds ratio (OR) 2.01 (95% confidence interval [CI] 1.01\u20133.69), but this relationship was not significant when headache days were accounted for, OR 2.02 (95% CI 0.83\u20134.91). Neither a history of a depression disorder, OR 1.40 (95% CI 0.90\u20132.16), nor an anxiety disorder, OR 1.11 (95% CI 0.71\u20131.72), was associated with taking medications early; however, duration of self\u2010monitoring was associated with taking MSM early, OR 1.006 (95% CI 1.004\u20131.009).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Lifetime history of depression and anxiety were not associated with taking a MSM early. Medication overuse may be more common in patients who have both migraine and anxiety. Taking a MSM early improved over time for all participants, even when adjusting for a history of an anxiety and or a depression disorder.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/head.14477","type":"journal-article","created":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T08:53:43Z","timestamp":1675846423000},"page":"368-376","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Lifetime history of an anxiety or depression disorder and adherence to medications used for the acute treatment of migraine"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8392-1328","authenticated-orcid":false,"given":"Nicole","family":"Butler","sequence":"first","affiliation":[{"name":"Ferkauf Graduate School of Psychology Yeshiva University  Bronx New York USA"},{"name":"Department of Psychiatry Weill Cornell Medical College\/New York\u2010Presbyterian  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivy C.","family":"Snyder","sequence":"additional","affiliation":[{"name":"Ferkauf Graduate School of Psychology Yeshiva University  Bronx New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Talia G.","family":"Korn","sequence":"additional","affiliation":[{"name":"Ferkauf Graduate School of Psychology Yeshiva University  Bronx New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2725-9739","authenticated-orcid":false,"given":"Robert A.","family":"Nicholson","sequence":"additional","affiliation":[{"name":"Medical Affairs, Neuroscience Business Unit Eli Lilly and Company  Indianapolis Indiana USA"},{"name":"Previously Affiliated at Mercy Health  St. Louis Missouri USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5426-5333","authenticated-orcid":false,"given":"Matthew S.","family":"Robbins","sequence":"additional","affiliation":[{"name":"Department of Neurology Weill Cornell Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8938-4949","authenticated-orcid":false,"given":"Elizabeth K.","family":"Seng","sequence":"additional","affiliation":[{"name":"Ferkauf Graduate School of Psychology Yeshiva University  Bronx New York USA"},{"name":"Saul R. Korey Department of Neurology Albert Einstein College of Medicine  Bronx New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,2,8]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000252808.97649.21"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102413485658"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra050100"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2009.01535.x"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(01)00457-7"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2003.03006.x"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2006.00581.x"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.12140"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2016.124"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2009.01343.x"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102416663459"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.14153"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2008.01217.x"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000335946.53860.1d"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2000.00018.x"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.12499"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2005.05107.x"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/2042098614522683"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2012.02223.x"},{"key":"e_1_2_11_21_1","unstructured":"Facts & Statistics: Anxiety and Depression Association of America ADAA. Accessed November 9 2022.https:\/\/adaa.org\/understanding\u2010anxiety\/facts\u2010statistics"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2020.569405"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2015-312233"},{"key":"e_1_2_11_24_1","unstructured":"Depression.2021. Accessed November 9 2022.https:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/depression"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-3787(05)85113-6"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2011.08.018"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2005.09.010"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/1129-2377-14-49"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10194-007-0361-3"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-011-1704-y"},{"issue":"7","key":"e_1_2_11_31_1","first-page":"1","article-title":"Classification and diagnostic criteria for headache disorders, cranial neuralgias and facial pain","volume":"8","author":"Headache Classification Committee of the International Headache Society","year":"1988","journal-title":"Cephalalgia"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11414-011-9234-2"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11886-016-0771-4"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2015.03.014"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1159\/000435931"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.1998.1807455.x"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2017.09.022"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"volume-title":"Tracking for Health","year":"2013","author":"Fox S","key":"e_1_2_11_39_1"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jada.2010.10.008"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(01)00742-2"},{"key":"e_1_2_11_42_1","article-title":"Self\u2010monitoring of blood glucose in patients with type 2 diabetes mellitus who are not using insulin","volume":"1","author":"Malanda UL","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5868-5-54"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(11)60561-2"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000200117"}],"container-title":["Headache: The Journal of Head and Face Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/head.14477","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/head.14477","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/headachejournal.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/head.14477","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T08:58:58Z","timestamp":1762073938000},"score":1,"resource":{"primary":{"URL":"https:\/\/headachejournal.onlinelibrary.wiley.com\/doi\/10.1111\/head.14477"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,8]]},"references-count":44,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["10.1111\/head.14477"],"URL":"https:\/\/doi.org\/10.1111\/head.14477","archive":["Portico"],"relation":{},"ISSN":["0017-8748","1526-4610"],"issn-type":[{"type":"print","value":"0017-8748"},{"type":"electronic","value":"1526-4610"}],"subject":[],"published":{"date-parts":[[2023,2,8]]},"assertion":[{"value":"2022-08-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}