{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T11:48:35Z","timestamp":1791460115343,"version":"4.3.4"},"reference-count":28,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T00:00:00Z","timestamp":1675814400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["headachejournal.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Headache"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess the prognostic impact of migraine headache in idiopathic intracranial hypertension (IIH).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Migraine headache is common in IIH, but it is unclear whether it has prognostic relevance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We investigated patients with IIH from the Vienna\u2010IIH\u2010database and differentiated migraine (IIH\u2010MIG) from non\u2010migraine headache (IIH\u2010nonMIG) and without headache (IIH\u2010noHA). Using multivariable models, we analyzed the impact of IIH\u2010MIG on headache and visual outcomes 12\u2009months after diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 97 patients (89% female, mean [SD] age 32.9\u00a0[11.1]\u00a0years, median body mass index 32.0\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      , median cerebrospinal fluid opening pressure 310\u2009mm), 46% were assigned to IIH\u2010MIG, 37% to IIH\u2010nonMIG (11% tension\u2010type, 26% unclassifiable), and 17% to IIH\u2010noHA. Overall, headache improvement was achieved in 77% and freedom of headache in 28%. The IIH\u2010MIG group showed significantly lower rates for headache improvement (67% vs. 89% in IIH\u2010nonMIG,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.019) and freedom of headache (11% vs. 33% in IIH\u2010nonMIG and 63% in IIH\u2010noHA,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.015). These differences persisted when only analyzing patients with resolved papilledema at follow\u2010up. In contrast, visual worsening was significantly less common in IIH\u2010MIG (9% vs. 28% in IIH\u2010nonMIG and 31% in IIH\u2010noHA,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.045). In multivariable models, IIH\u2010MIG was associated with a significantly lower likelihood of achieving headache improvement (odds ratio [OR] 0.57, 95% confidence interval [CI] 0.40\u20130.78,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and freedom of headache (OR 0.29, 95% CI 0.12\u20130.46,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), but also a lower risk for visual worsening (OR 0.26, 95% CI 0.04\u20130.82,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In IIH, migraine headache is associated with unfavorable outcomes for headache, even when papilledema has resolved, and possibly favorable visual outcome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/head.14478","type":"journal-article","created":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T10:43:11Z","timestamp":1675852991000},"page":"601-610","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Idiopathic intracranial hypertension presenting with migraine phenotype is associated with unfavorable headache outcomes"],"prefix":"10.1111","volume":"63","author":[{"given":"Gabriel","family":"Bsteh","sequence":"first","affiliation":[{"name":"Department of Neurology Medical University of Vienna  Vienna Austria"},{"name":"Comprehensive Center for Clinical Neurosciences &amp; Mental Health Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Macher","sequence":"additional","affiliation":[{"name":"Department of Neurology Medical University of Vienna  Vienna Austria"},{"name":"Comprehensive Center for Clinical 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