{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T22:31:36Z","timestamp":1791585096046,"version":"4.3.4"},"reference-count":20,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T00:00:00Z","timestamp":1683158400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000038","name":"U.S. Food and Drug Administration","doi-asserted-by":"publisher","award":["UH3FD006795"],"award-info":[{"award-number":["UH3FD006795"]}],"id":[{"id":"10.13039\/100000038","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["headachejournal.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Headache"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>There is renewed emphasis on including patients in determining, defining, and prioritizing outcomes for migraine treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To obtain insights directly from people living with migraine on their priorities for treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 40 qualitative interviews were conducted as part of the Migraine Clinical Outcome Assessment System project, a United States Food and Drug Administration grant\u2010funded program to develop a core set of patient\u2010centered outcome measures for migraine clinical trials. Interviews included a structured exercise in which participants rank\u2010ordered pre\u2010defined lists of potential benefits for acute and preventive migraine therapy. The 40 study participants who reported being diagnosed with migraine by a clinician ranked the benefits and explained their rationale.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Study participants consistently ranked either pain relief or absence of pain as their top priority for acute treatment. Relief\/absence of other migraine symptoms and improved functioning were also prioritized. For preventive treatment, participants prioritized reductions in migraine frequency, symptom severity, and attack duration. Few differences were found between participants with episodic migraine and those with chronic migraine. However, participants with chronic migraine ranked \u201cincreased predictability of attacks\u201d much higher than those with episodic migraine. Participants' rankings were influenced by prior expectations and experiences of migraine treatments, which caused many participants to deprioritize desired benefits as unrealistic. Participants also identified several additional priorities, including limited side\u2010effects and reliable treatment efficacy in both acute and preventive treatments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The results showed the participants prioritized treatment benefits aligned with existing core clinical outcomes used in migraine research, but also valued benefits that are not typically assessed, such as predictability. Participants also deprioritized important benefits when they believed treatment was unlikely to deliver those outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/head.14521","type":"journal-article","created":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T07:45:29Z","timestamp":1683186329000},"page":"953-964","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Priority acute and preventive migraine treatment benefits: Results of the Migraine Clinical Outcome Assessment System\n                    <scp>(MiCOAS)<\/scp>\n                    qualitative study of people living with migraine"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6231-5890","authenticated-orcid":false,"given":"Rikki","family":"Mangrum","sequence":"first","affiliation":[{"name":"Vector Psychometric Group  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2035-0828","authenticated-orcid":false,"given":"Maya T.","family":"Gerstein","sequence":"additional","affiliation":[{"name":"Patient Centered Outcomes Open Health Group  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"Calvin J.","family":"Hall","sequence":"additional","affiliation":[{"name":"Vector Psychometric Group  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawn C.","family":"Buse","sequence":"additional","affiliation":[{"name":"Vector Psychometric Group  Chapel Hill North Carolina USA"},{"name":"Neurology Albert Einstein College of Medicine  Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carrie R.","family":"Houts","sequence":"additional","affiliation":[{"name":"Vector Psychometric Group  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James S.","family":"McGinley","sequence":"additional","affiliation":[{"name":"Vector Psychometric Group  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly P.","family":"McCarrier","sequence":"additional","affiliation":[{"name":"Patient Centered Outcomes Open Health Group  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2652-2897","authenticated-orcid":false,"given":"Richard B.","family":"Lipton","sequence":"additional","affiliation":[{"name":"Neurology Albert Einstein College of Medicine  Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. J.","family":"Wirth","sequence":"additional","affiliation":[{"name":"Vector Psychometric Group  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,4]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1474-4422(18)30322-3"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2001.041007646.x"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000252808.97649.21"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-022-01439-3"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.CON.0000418641.45522.3b"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102417738202"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.13165"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.14312"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-022-01463-3"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0098933"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2005.00797.x"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.13978"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1185\/030079905x36387"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.14067"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.14069"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102417731348"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-012-0263-1"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000078940.53438.83"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.252.14.1905"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1586\/erp.10.30"}],"container-title":["Headache: The Journal of Head and Face Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/headachejournal.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/head.14521","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T11:00:17Z","timestamp":1762081217000},"score":1,"resource":{"primary":{"URL":"https:\/\/headachejournal.onlinelibrary.wiley.com\/doi\/10.1111\/head.14521"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,4]]},"references-count":20,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["10.1111\/head.14521"],"URL":"https:\/\/doi.org\/10.1111\/head.14521","archive":["Portico"],"relation":{},"ISSN":["0017-8748","1526-4610"],"issn-type":[{"value":"0017-8748","type":"print"},{"value":"1526-4610","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,4]]},"assertion":[{"value":"2022-10-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}