{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T17:09:40Z","timestamp":1790701780176,"version":"4.1.0"},"reference-count":34,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T00:00:00Z","timestamp":1721088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["headachejournal.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Headache"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Post\u2010dural puncture headache (PDPH) is a frequent complication following lumbar puncture, epidural analgesia, or neuraxial anesthesia. The International Classification of Headache Disorders, third edition categorizes PDPH as a self\u2010limiting condition; however, emerging evidence, including our findings, suggests that PDPH can have a prolonged course, challenging this traditional view.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To elucidate the diagnostic characteristics and treatment outcomes of persistent PDPH (pPDPH), offering insights into its demographic profiles and diagnostic features.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We executed an anonymous, web\u2010based survey targeting individuals aged \u226518\u2009years diagnosed with or suspected of having pPDPH. Recruitment occurred through self\u2010help groups on Facebook. The survey comprised questions regarding diagnostic procedures, treatment regimens, outcomes, and healthcare consultation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The survey achieved a response rate of 179\/347 (51.6%) individuals completing the questionnaire. Cerebrospinal fluid (CSF) leaks were confirmed in nine of 179 (5.0%) cases. Signs of intracranial hypotension without a CSF leak were observed in 70\/179 (39.1%) individuals. All participants underwent magnetic resonance imaging scans of the brain and spine, with computed tomography myelography performed in 113\/179 (63.1%) cases. Medications, including analgesics, theophylline, and gabapentin, provided minimal short\u2010term relief. Epidural blood patch treatments resulted in slight\u2010to\u2010moderate short\u2010term improvement in 136\/179 (76.0%), significant improvement in 22\/179 (12.3%), and complete effectiveness in eight of 179 (4.5%) individuals. For long\u2010term outcomes, slight\u2010to\u2010moderate improvement was reported by 118\/179 (66.0%) individuals. Surgical interventions were carried out in 42\/179 (23.5%) patients, revealing pseudomeningoceles intraoperatively in 20\/42 (47.6%) individuals. After surgery, 21\/42 (50.0%) of the participants experienced slight\u2010to\u2010moderate improvement, 12\/42 (28.6%) showed more pronounced improvement, and five of the 42 (11.9%) achieved complete effectiveness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study underscores the complexities of managing pPDPH. The delay in diagnosis can impact the effectiveness of treatments, including epidural blood patch and surgical interventions, resulting in ongoing symptoms. This underscores the importance of tailored and adaptable treatment strategies. The findings advocate for additional research to deepen the understanding of pPDPH and improve long\u2010term patient outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/head.14790","type":"journal-article","created":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T08:39:50Z","timestamp":1721119190000},"page":"1015-1026","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Diagnostic and therapeutic insights in individuals with persistent post\u2010dural puncture headache: A cross\u2010sectional study"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4007-0973","authenticated-orcid":false,"given":"Ali","family":"Kapan","sequence":"first","affiliation":[{"name":"Department of Social and Preventive Medicine, Center for Public Health Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Waldh\u00f6r","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Center for Public Health Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Schiffler","sequence":"additional","affiliation":[{"name":"Department of Social and Preventive Medicine, Center for Public Health Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7687-6098","authenticated-orcid":false,"given":"J\u00fcrgen","family":"Beck","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery University Medical Center Freiburg  Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"W\u00f6ber","sequence":"additional","affiliation":[{"name":"Department of Neurology Medical University of Vienna  Vienna Austria"},{"name":"Comprehensive Center for Clinical Neurosciences and Mental Health Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,16]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102417738202"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.15491"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e3182501c06"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000004336"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2014.07.008"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/rapm-2023-104817"},{"key":"e_1_2_11_8_1","first-page":"71","article-title":"Management and outcomes of persistent headache after accidental dural puncture in the obstetric population: a 9\u2010year prospective audit. 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