{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T19:58:48Z","timestamp":1790798328329,"version":"4.1.0"},"reference-count":132,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T00:00:00Z","timestamp":1722211200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["K23 NS124986"],"award-info":[{"award-number":["K23 NS124986"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["headachejournal.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Headache"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To provide healthcare professionals guidance on youth at risk for prolonged recovery and post\u2010traumatic headache (PTH), and on pharmacologic and non\u2010pharmacologic management of PTH due to concussion and mild traumatic brain injury.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Headache is the most common persistent post\u2010concussive symptom affecting 8% of youth for &gt;3\u2009months after concussion. Over the past decade, many studies have explored the treatment of PTH in youth, but there are no established guidelines.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This white paper is based on a synthesis of an updated systematic review of the literature on treatment of PTH and a narrative review of the literature on risk factors for prolonged recovery and health disparities. Results were interpreted by a group of expert providers in PTH in children and adolescents through collaboration of the PTH and pediatric special interest groups of the American Headache Society.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Factors that consistently were associated with prolonged recovery from concussion and persistent PTH included female sex, a high number of acute symptoms, and adolescent age. Social determinants of health also likely play an important role in PTH and deserve consideration in the clinical and research settings. A total of 33 studies met the criteria for inclusion in the systematic review of PTH treatment in youth, although most were retrospective and of fair\u2010to\u2010poor quality. Treatment strategies included acute and preventive pharmacologic management, procedures, neuro\u2010modulatory devices, physical therapy, physical activity, and behavioral health support. A collaborative care approach that includes a thoughtful combination of these management strategies is likely most effective.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This white paper provides a roadmap for tailoring the treatment of PTH based on factors influencing prolonged headache, the timing of therapies, and therapies with the most evidence for treating PTH in youth. We also highlight research needed for developing more definitive guidelines on PTH management in youth.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/head.14795","type":"journal-article","created":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T08:44:02Z","timestamp":1722242642000},"page":"1148-1162","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["American Headache Society white paper on treatment of post\u2010traumatic headache from concussion in youth"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4996-2457","authenticated-orcid":false,"given":"Carlyn","family":"Patterson\u00a0Gentile","sequence":"first","affiliation":[{"name":"Division of Pediatric Neurology Children's Hospital of Philadelphia  Philadelphia Pennsylvania USA"},{"name":"Departments of Neurology and Pediatrics University of Pennsylvania Perelman School of Medicine  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Rosenthal","sequence":"additional","affiliation":[{"name":"Department of Pediatrics \u2010 Neurology Children's Hospital Colorado  Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidi","family":"Blume","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurology Seattle Children's Hospital University of Washington School of Medicine  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reena Gogia","family":"Rastogi","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurology Barrow Neurological Institute at Phoenix Children's Hospital  Phoenix Arizona USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0018-1644","authenticated-orcid":false,"given":"Jennifer","family":"McVige","sequence":"additional","affiliation":[{"name":"Pediatric Neurology, Pediatric and Adult Headache Dent Neurologic Institute  Amherst New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alma","family":"Bicknese","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurology Department of Pediatrics Ann &amp; Robert H. 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