{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T20:45:27Z","timestamp":1782938727903,"version":"3.54.5"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,11,22]],"date-time":"2024-11-22T00:00:00Z","timestamp":1732233600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["headachejournal.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Headache"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Lemierre syndrome is a life\u2010threatening but treatable septic thrombosis of the internal jugular vein (IJV) derived from a craniocervical bacterial infection. Metastatic septic embolization is common. However, diagnostic delay and poor prognosis remain a problem, largely due to the diverse clinical presentations and unclear symptomatology of Lemierre syndrome. In contrast, occipital neuralgia is a common disease typically treated with symptomatic therapy in emergency settings, as most cases are not life\u2010threatening. The present case involved a 70\u2010year\u2010old female with Lemierre syndrome stemming from\n                    <jats:italic>Streptococcus anginosus<\/jats:italic>\n                    infection originating in sinusitis or periodontitis. The onset was characterized by headache with typical occipital neuralgia, a severe trigger point in the posterior neck ipsilateral to the infected IJV, and reduced sensation of the C2 nerve root area. Given the anatomical relationship of the cranial venous emissary system into the posterior cervical venous plexus, the case highlights the potential for the neighboring occipital nerve to be directly involved in Lemierre syndrome. Interestingly, despite Lemierre syndrome typically arising from pharyngeal bacterial infections and infected IJV located in the \u201canterior\u201d neck, many prior case reports have described \u201coccipital\u201d or \u201cposterior\u201d pain at the head or neck. History taking and physical examination remain essential to identify the causes of these posterior\/occipital symptoms, since imaging investigations, as in this case, often fail to identify them. Early recognition of occipital neuralgia as a potential initial symptom of Lemierre syndrome could lead to earlier diagnosis and treatment, potentially improving patient outcomes.\n                  <\/jats:p>","DOI":"10.1111\/head.14876","type":"journal-article","created":{"date-parts":[[2024,11,22]],"date-time":"2024-11-22T06:08:12Z","timestamp":1732255692000},"page":"897-901","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Occipital neuralgia as an initial manifestation of atypical Lemierre syndrome: A case report"],"prefix":"10.1111","volume":"65","author":[{"given":"Akira","family":"Hanazono","sequence":"first","affiliation":[{"name":"Department of Neurology Akita University Graduate School of Medicine  Akita Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keita","family":"Yasuda","sequence":"additional","affiliation":[{"name":"Department of Neurology Akita University Graduate School of 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