{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T00:08:34Z","timestamp":1785024514513,"version":"3.55.0"},"reference-count":32,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T00:00:00Z","timestamp":1747699200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["headachejournal.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Headache"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study aimed to evaluate the effects of different types and combinations of exercise on migraine attacks and accompanying comorbidities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Combining aerobic and resistance exercises may yield more significant improvements in patients with migraine.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This parallel\u2010group randomized controlled study included 24 participants, who were then divided equally into three groups: an aerobic exercise group, a combined exercise group (aerobic and resistance exercises), and a control group. It was conducted at Ege University Hospital between September 2022 and March 2024. Following a 1\u2010month baseline headache diary period, both intervention groups participated in the same aerobic exercises 3\u2009days a week for 12\u2009weeks. The combined exercise group performed five resistance exercises targeting the neck, upper back, and shoulder muscles alongside the aerobic exercises 3\u2009days a week for 12\u2009weeks. Measurements were taken at baseline, after the 3\u2010month intervention period, and after a 2\u2010month follow\u2010up period. The primary outcome was the number of migraine headache days per month. Secondary outcomes included anxiety and depression levels, aerobic capacity, physical activity status, and migraine\u2010related quality of life.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The number of migraine days per month significantly decreased in both the aerobic and combined exercise groups during the post\u2010intervention period, while no significant change was observed in the control group (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001 for aerobic and combined exercise groups, <jats:italic>p<\/jats:italic>\u2009=\u20090.166 for control group). Migraine headache frequency showed a statistically significant decrease in the combined exercise group compared to the aerobic exercise group (<jats:italic>p<\/jats:italic>\u2009=\u20090.027). Additionally, both exercise groups showed significant improvements in aerobic capacity (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001 for both) and physical activity levels (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001 and <jats:italic>p<\/jats:italic>\u2009=\u20090.001, respectively) post\u2010intervention, which were not observed in the control group (<jats:italic>p<\/jats:italic>\u2009=\u20090.747 for aerobic capacity, <jats:italic>p<\/jats:italic>\u2009=\u20090.05 for physical activity levels). Although no significant effect on depression scores was observed in either exercise group, anxiety scores significantly decreased in the combined exercise group from pre\u2010 to post\u2010intervention (<jats:italic>p<\/jats:italic>\u2009=\u20090.037). Significant improvements in migraine\u2010related quality of life were observed in both intervention groups (<jats:italic>p<\/jats:italic>\u2009=\u20090.018 and <jats:italic>p<\/jats:italic>\u2009=\u20090.001, respectively), with no significant difference (<jats:italic>p<\/jats:italic>\u2009=\u20090.934). Neither significant change was observed in depression and anxiety scores nor migraine\u2010related quality of life in the control group (<jats:italic>p<\/jats:italic>\u2009=\u20090.593, <jats:italic>p<\/jats:italic>\u2009=\u20090.438 and 0.081 respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Aerobic and combined exercise groups showed a reduction in monthly migraine headache frequency without any side effects, with the reduction being statistically more significant in the combined exercise group.<\/jats:p><\/jats:sec>","DOI":"10.1111\/head.14951","type":"journal-article","created":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T07:17:02Z","timestamp":1747725422000},"page":"1593-1602","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The effect of different exercise types on migraine frequency in individuals with migraine: A pilot study"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8665-9361","authenticated-orcid":false,"given":"Yunus Emre","family":"Meydanal","sequence":"first","affiliation":[{"name":"Department of Sport Medicine, Faculty of Medicine Ege University  Bornova Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Se\u00e7kin","family":"\u015een\u0131\u015f\u0131k","sequence":"additional","affiliation":[{"name":"Department of Sport Medicine, Faculty of Medicine Ege University  Bornova Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hadiye","family":"\u015eirin","sequence":"additional","affiliation":[{"name":"Department of Neurology Ege University  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,20]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2008.01678.x"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2007.01279.x"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2008.01782.x"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2012.02223.x"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1819.2012.02405.x"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-012-1029-6"},{"issue":"1","key":"e_1_2_13_8_1","first-page":"105","article-title":"Psychiatric comorbidity in migraine","volume":"30","author":"\u0160agud M","year":"2021","journal-title":"Medicus"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2009.01608.x"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2004.06.002"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2006.00684.x"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.12644"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2008.01231.x"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102411419681"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/PHM.0000000000001349"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/sms.13023"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102418758283"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2004.04146.x"},{"issue":"1","key":"e_1_2_13_19_1","first-page":"280","article-title":"Hastane Anksiyete ve Depresyon \u00d6l\u00e7e\u011fi T\u00fcrk\u00e7e Formunun Ge\u00e7erlilik ve G\u00fcvenilirlik \u00c7al\u0131\u015fmas\u0131. 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