{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T07:15:02Z","timestamp":1770275702878,"version":"3.49.0"},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,3,12]],"date-time":"2014-03-12T00:00:00Z","timestamp":1394582400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Helicobacter"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p><jats:italic>Helicobacter pylori<\/jats:italic> (<jats:italic>H. pylori)<\/jats:italic> testing in patients with bleeding ulcers is recommended by society guidelines and considered a quality indicator. The aim of the study is to examine the proportion of patients with bleeding ulcers who had <jats:italic>H. pylori<\/jats:italic> testing and identify predictors associated with <jats:italic>H. pylori<\/jats:italic> testing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Consecutive hospitalized patients with bleeding ulcers documented endoscopically at a single center from 10\/2004\u20105\/2011 were identified retrospectively from an endoscopy database. The proportion of patients undergoing direct <jats:italic>H. pylori<\/jats:italic> testing (histology, rapid urease test, breath test or stool antigen) and any <jats:italic>H. pylori<\/jats:italic> testing (direct or serologic) were determined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 330 patients with bleeding ulcers, 105 (32%, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 27\u201337%) underwent direct testing and another 52 (16%, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 12\u201320%) had serologic testing during a median follow\u2010up of 9\u00a0months (range, 0\u201386). <jats:italic>H. pylori<\/jats:italic> testing occurred at the index hospitalization in 146 (93%) of the 157 patients tested. Among the 105 patients who had direct <jats:italic>H. pylori<\/jats:italic> testing, 90 (86%) had biopsy\u2010based testing during the initial endoscopy. On multivariate analysis, undergoing biopsy of a gastric ulcer was strongly associated with having direct <jats:italic>H. pylori<\/jats:italic> testing performed (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a05.1, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 2.3\u201311.5; <jats:italic>p\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Among patients hospitalized with bleeding ulcers, less than half received <jats:italic>H. pylori<\/jats:italic> testing and less than a third received the more accurate direct testing. Most of the direct <jats:italic>H. pylori<\/jats:italic> testing was biopsy\u2010based with very few being tested after the index hospitalization. Efforts to increase <jats:italic>H. pylori<\/jats:italic> testing in patients with bleeding ulcers are needed to improve outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hel.12114","type":"journal-article","created":{"date-parts":[[2014,3,12]],"date-time":"2014-03-12T11:15:13Z","timestamp":1394622913000},"page":"98-104","source":"Crossref","is-referenced-by-count":14,"title":["Low Adherence to <i>Helicobacter pylori<\/i> Testing in Hospitalized Patients with Bleeding Peptic Ulcer Disease"],"prefix":"10.1111","volume":"19","author":[{"given":"John J.","family":"Kim","sequence":"first","affiliation":[{"name":"Loma Linda University Global Health Institute Loma Linda CA USA"},{"name":"Sir Run Run Shaw Hospital Zhejiang University Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John S.","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Loma Linda University Medical Center Loma Linda CA 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