{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T01:51:43Z","timestamp":1780105903658,"version":"3.54.0"},"reference-count":53,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,5,5]],"date-time":"2014-05-05T00:00:00Z","timestamp":1399248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Helicobacter"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p><jats:italic>Helicobacter pylori<\/jats:italic> (<jats:italic><jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>.\u00a0pylori<\/jats:italic>) infection is the most common chronic bacterial infection in humans. Its prevalence in <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>mani adults and children is not known.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To report histology\u2010based <jats:italic><jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>.\u00a0pylori<\/jats:italic> infection prevalence in <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>mani children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective study of biopsy proven <jats:italic><jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>.\u00a0pylori<\/jats:italic> infection in children over a 3\u00a0year period in a single center. Age, gender, indication for endoscopy, history of recurrent abdominal pain, and anemia were compared between <jats:italic><jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>.\u00a0pylori<\/jats:italic>\u2010positive and negative children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 143 patients who underwent endoscopy, gastric biopsies were available on 112. The overall prevalence of biopsy proven <jats:italic><jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>.\u00a0pylori<\/jats:italic> infection was 25%. The prevalence in children with recurrent abdominal pain was 30% compared to 22% in children who underwent endoscopy for other indications (<jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>.382). The prevalence increased from 7% in children aged &lt;5\u00a0years, to 33% in those aged between 5 and 10\u00a0years (<jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>.010). There was no significant difference in the prevalence between the 5\u201310\u00a0years age group (33%) and older age group (29%) (<jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>.814). There was no significant difference in gender or anemia between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study represents the first reported study on the prevalence of biopsy proven <jats:italic><jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>.\u00a0pylori<\/jats:italic> infection in <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>mani children. <jats:italic><jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>.\u00a0pylori<\/jats:italic> infection prevalence is 25%, is lower than regional and many <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>rab countries. The prevalence appears to increase till age of 5\u00a0years. There was no significant association between <jats:italic><jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>.\u00a0pylori<\/jats:italic> and recurrent abdominal pain, gender, or anemia.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hel.12134","type":"journal-article","created":{"date-parts":[[2014,5,5]],"date-time":"2014-05-05T04:36:46Z","timestamp":1399264606000},"page":"306-311","source":"Crossref","is-referenced-by-count":8,"title":["<i>Helicobacter Pylori<\/i> Infection in Omani Children"],"prefix":"10.1111","volume":"19","author":[{"given":"Siham","family":"Al\u2010Sinani","sequence":"first","affiliation":[{"name":"Gastroenterology Unit Department of Child Health Sultan Qaboos University Hospital Muscat Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharef W.","family":"Sharef","sequence":"additional","affiliation":[{"name":"Gastroenterology Unit Department of Child Health Sultan Qaboos University Hospital Muscat Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalid","family":"Al\u2010Naamani","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Department of Internal Medicine Armed Forces Hospital Muscat Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyatt","family":"Al\u2010Sharji","sequence":"additional","affiliation":[{"name":"Gastroenterology Unit Department of Child Health Sultan Qaboos University Hospital Muscat 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