{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T17:59:45Z","timestamp":1771955985171,"version":"3.50.1"},"reference-count":38,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2017,9,10]],"date-time":"2017-09-10T00:00:00Z","timestamp":1505001600000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Helicobacter"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A substantial decrease in <jats:italic>Helicobacter pylori\u2010<\/jats:italic>associated peptic ulcer disease has been observed during the last decades. Drug\u2010related ulcers as well as idiopathic ulcers are becoming predominant and are more refractory to treatment; however, <jats:italic>H. pylori<\/jats:italic> infection still plays an important role in ulcer bleeding and recurrence after therapy. The effect of <jats:italic>H. pylori<\/jats:italic> eradication upon functional dyspepsia symptoms has been reviewed in this article and generally confirms the results of previous meta\u2010analyses. Additional evidence suggests a lack of impact upon the quality of life, in spite of improvement in symptoms. The association of <jats:italic>H. pylori<\/jats:italic> with gastroesophageal reflux disease and Barrett's esophagus remains controversial with a majority of published studies showing a negative association. Furthermore, a strong inverse relationship between the presence of <jats:italic>H. pylori<\/jats:italic> and the esophageal eosinophilia was also reported. Several studies and a review addressed the role of <jats:italic>H. pylori<\/jats:italic> in autoimmune gastritis and pernicious anemia. The association of the above still remains controversial. Finally, the necessity of routine endoscopy and <jats:italic>H. pylori<\/jats:italic> eradication before bariatric surgery is discussed. Several studies suggest the rationale of preoperative upper endoscopy and <jats:italic>H. pylori<\/jats:italic> eradication prior to surgery. However, the prevalence of <jats:italic>H. pylori<\/jats:italic> infection prior to surgery in these studies generally reflects the overall prevalence of the infection in the particular geographic area. In addition, results on the role of <jats:italic>H. pylori<\/jats:italic> in developing postoperative complications remain controversial.<\/jats:p>","DOI":"10.1111\/hel.12408","type":"journal-article","created":{"date-parts":[[2017,9,11]],"date-time":"2017-09-11T02:05:15Z","timestamp":1505095515000},"source":"Crossref","is-referenced-by-count":26,"title":["<i>Helicobacter pylori<\/i> infection and nonmalignant diseases"],"prefix":"10.1111","volume":"22","author":[{"given":"Olga","family":"Sjomina","sequence":"first","affiliation":[{"name":"Institute of Clinical and Preventive Medicine &amp; Faculty of Medicine University of Latvia  Riga Latvia"},{"name":"Riga East University Hospital  Riga Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederic","family":"Heluwaert","sequence":"additional","affiliation":[{"name":"Hepato\u2010gastroenterology department Annecy Genevois Hospital  Pringy 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