{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:34:19Z","timestamp":1753878859670,"version":"3.41.2"},"reference-count":40,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,10,5]],"date-time":"2017-10-05T00:00:00Z","timestamp":1507161600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Helicobacter"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To compare retinal nerve fiber layer thicknesses (<jats:styled-content style=\"fixed-case\">RNFLT<\/jats:styled-content>) of patients with or without <jats:italic>Helicobacter pylori<\/jats:italic> infection and to reveal the possible <jats:styled-content style=\"fixed-case\">RNFLT<\/jats:styled-content> changes after <jats:italic>H.\u00a0pylori<\/jats:italic> eradication.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Sixty\u2010five eyes of 65 patients that tested positive for <jats:italic>H.\u00a0pylori<\/jats:italic> (Group 1) and 48 eyes of 48 patients that tested negative for <jats:italic>H.\u00a0pylori<\/jats:italic> (Group 2) were included. <jats:styled-content style=\"fixed-case\">RNFLT<\/jats:styled-content> analyses were performed with spectral\u2010domain (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>) optical coherence tomography (<jats:styled-content style=\"fixed-case\">OCT<\/jats:styled-content>) in a total of five regions: the superior, inferior, nasal, and temporal quadrants and the average. Then, a comparison was made between groups. After <jats:italic>H.\u00a0pylori<\/jats:italic> eradication in 38 patients, <jats:styled-content style=\"fixed-case\">RNFLT<\/jats:styled-content>s were compared with both pre\u2010eradication values and Group 2.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The groups were similar in terms of age and gender. Temporal quadrant <jats:styled-content style=\"fixed-case\">RNFLT<\/jats:styled-content> was thinner in Group 1 than in Group 2 (<jats:italic>P<\/jats:italic>=.02). After <jats:italic>H.\u00a0pylori<\/jats:italic> eradication, <jats:styled-content style=\"fixed-case\">RNFLT<\/jats:styled-content>s did not differ from pre\u2010eradication values in Group 1 (<jats:italic>P<\/jats:italic>&gt;.05 for all), whereas temporal quadrant <jats:styled-content style=\"fixed-case\">RNFLT<\/jats:styled-content> after <jats:italic>H.\u00a0pylori<\/jats:italic> eradication was thinner compared to Group 2 (<jats:italic>P<\/jats:italic>=.03).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:italic>H.\u00a0pylori<\/jats:italic> may cause the localized defects on <jats:styled-content style=\"fixed-case\">RNFL<\/jats:styled-content> that are the early signs of glaucoma.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hel.12443","type":"journal-article","created":{"date-parts":[[2017,10,5]],"date-time":"2017-10-05T13:59:34Z","timestamp":1507211974000},"source":"Crossref","is-referenced-by-count":1,"title":["Are optic nerve heads of patients with helicobacter pylori infection more susceptible to glaucomatous damage?"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8875-1567","authenticated-orcid":false,"given":"Cemile Ucgul","family":"Atilgan","sequence":"first","affiliation":[{"name":"Ankara Ulucanlar Eye Training and Research Hospital  Altindag\/Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pinar","family":"Kosekahya","sequence":"additional","affiliation":[{"name":"Ankara Ulucanlar Eye Training and Research Hospital  Altindag\/Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"Yozgat","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Ankara Numune Training and Research Hospital  Altindag\/Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emine","family":"Sen","sequence":"additional","affiliation":[{"name":"Ankara Ulucanlar Eye Training and Research Hospital  Altindag\/Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nilufer","family":"Berker","sequence":"additional","affiliation":[{"name":"Ankara Ulucanlar Eye Training and Research Hospital  Altindag\/Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehtap","family":"Caglayan","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Mardin State Hospital  Mardin Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selam Yekta","family":"Sendul","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Sisli Etfal Training and Research Hospital  Sisli\/Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emin","family":"Altiparmak","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Ankara Numune Training and Research Hospital  Altindag\/Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pelin","family":"Yilmazbas","sequence":"additional","affiliation":[{"name":"Ankara Ulucanlar Eye Training and Research Hospital  Altindag\/Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,10,5]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"388","article-title":"Evidence based medicine and extradigestive manifestation of Helicobacter Pylori","volume":"63","author":"Koster E","year":"2000","journal-title":"Acta Gastroenterol Belg"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-005-7205-3"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.05-0323"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2008.150409"},{"key":"e_1_2_7_6_1","first-page":"1021","article-title":"Role de I' Helicobacter pylori dans la chorioretinopathie sereuse centrale et I'epitheliopathie retinienne diffuse (Helicobacter pylori in central serous chorioretinopathy and diffuse retinal epitheliopathy. 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