{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T07:07:49Z","timestamp":1767164869322,"version":"build-2238731810"},"reference-count":40,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,7,4]],"date-time":"2018-07-04T00:00:00Z","timestamp":1530662400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Helicobacter"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Infections with gastric\n                      <jats:italic>Helicobacter<\/jats:italic>\n                      spp. are associated with gastritis, peptic ulceration, and malignancies.\n                      <jats:italic>Helicobacter pylori<\/jats:italic>\n                      is the most prevalent\n                      <jats:italic>Helicobacter<\/jats:italic>\n                      species colonizing the human stomach. Other gastric non\u2010\n                      <jats:italic>H.\u00a0pylori<\/jats:italic>\n                      helicobacters (\n                      <jats:styled-content style=\"fixed-case\">NHPH<\/jats:styled-content>\n                      s) have been described in 0.2%\u20106% of human patients with gastric disorders. Nevertheless, due to difficulties in the diagnosis of\n                      <jats:styled-content style=\"fixed-case\">NHPH<\/jats:styled-content>\n                      infections and lack of routine screening, this is most likely an underestimation of their true prevalence. To the best of our knowledge, no studies have been performed in the presence of\n                      <jats:italic>Helicobacter<\/jats:italic>\n                      spp. in children suffering from gastric disorders in Southern Turkey.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>\n                      In total, 110 children with gastric complaints were examined at the Cukurova University Balcali hospital, Turkey. Gastroscopy was performed to evaluate the presence of gastric mucosal lesions. Biopsies of the pyloric gland zone were taken for histopathological analysis, rapid urease testing, and presence of\n                      <jats:italic>Helicobacter<\/jats:italic>\n                      spp.\n                      <jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content>\n                      by\n                      <jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Based on the\n                      <jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content>\n                      results, the prevalence of\n                      <jats:italic>Helicobacter<\/jats:italic>\n                      spp. was 32.7% (36\/110).\n                      <jats:italic>H.\u00a0pylori<\/jats:italic>\n                      was found in 30.9% (34\/110),\n                      <jats:italic>H.\u00a0suis<\/jats:italic>\n                      in 1.8% (2\/110), and\n                      <jats:italic>H.\u00a0heilmannii\/H.\u00a0ailurogastricus<\/jats:italic>\n                      in 0.9% (1\/110) of the human patients. A mixed infection with\n                      <jats:italic>H.\u00a0pylori<\/jats:italic>\n                      and\n                      <jats:italic>H.\u00a0suis<\/jats:italic>\n                      was present in one patient. The presence of mucosal abnormalities, such as nodular inflammation, ulceration, and hyperemia, as well as gastritis, was significantly higher in\n                      <jats:italic>Helicobacter<\/jats:italic>\n                      spp. positive patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Helicobacter pylori<\/jats:italic>\n                      ,\n                      <jats:italic>H.\u00a0suis<\/jats:italic>\n                      , and\n                      <jats:italic>H.\u00a0heilmannii\/H.\u00a0ailurogastricus<\/jats:italic>\n                      were present in children with gastric complaints. Infection with these pathogens may be involved in the development of gastritis and ulceration.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hel.12511","type":"journal-article","created":{"date-parts":[[2018,7,5]],"date-time":"2018-07-05T01:54:03Z","timestamp":1530755643000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Presence of gastric\n                    <i>Helicobacter<\/i>\n                    species in children suffering from gastric disorders in Southern Turkey"],"prefix":"10.1111","volume":"23","author":[{"given":"Ali","family":"Bahadori","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology Sarab Faculty of Medical Sciences  Sarab Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7632-105X","authenticated-orcid":false,"given":"Chlo\u00eb","family":"De 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