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The pooled odds ratios (ORs) with their corresponding 95% confidence intervals (CIs) were selected as the effect size. Subgroup analysis and sensitivity analysis were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010one studies with a total of 22\u00a0845 participants were identified. There was significant association of <jats:italic>H\u00a0pylori<\/jats:italic> infection with preeclampsia (OR: 2.51; 95% CI: 1.88\u20103.34; <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), fetal growth restriction (OR: 2.28; 95% CI: 1.21\u20104.32; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.01), gestational diabetes mellitus (OR: 2.03; 95% CI: 1.56\u20102.64; <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), spontaneous abortion (OR: 1.50; 95% CI: 1.05\u20102.14; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.024), and birth defect (OR: 1.63; 95% CI: 1.05\u20102.54; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.03). Sensitivity analysis showed the significant association between <jats:italic>H\u00a0pylori<\/jats:italic> infection and low birthweight (OR: 1.59; 95% CI: 1.05\u20102.40; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.03).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The present meta\u2010analysis offers proof to support that <jats:italic>H\u00a0pylori<\/jats:italic> infection during pregnancy can increase the risk on adverse pregnancy outcomes. Screening and treating for <jats:italic>H\u00a0pylori<\/jats:italic> infection before pregnancy should be taken into account.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hel.12562","type":"journal-article","created":{"date-parts":[[2019,1,24]],"date-time":"2019-01-24T04:28:23Z","timestamp":1548304103000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["The risk of <i>Helicobacter pylori<\/i> infection for adverse pregnancy outcomes: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7378-1915","authenticated-orcid":false,"given":"Yongle","family":"Zhan","sequence":"first","affiliation":[{"name":"School of Public Health Chinese Academy of Medical Sciences &amp; Peking Union Medical College Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingyu","family":"Si","sequence":"additional","affiliation":[{"name":"School 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