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Under such circumstances, JSHR has made the third revision to the \u201cGuidelines for diagnosis and treatment of\n                      <jats:italic>H. pylori<\/jats:italic>\n                      infection\u201d for the first time in 7\u00a0years.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The Guideline Committee held 10 meetings. Articles published between the establishment of the 2009 Guidelines and March 2016 were reviewed and classified according to the evidence level; the statements were revised on the basis of this review. After inviting public comments, the revised statements were finalized using the Delphi method.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There was no change in the basic policy that\n                      <jats:italic>H. pylori<\/jats:italic>\n                      infectious disease is an indication for eradication. Other diseases presumed to be associated with\n                      <jats:italic>H. pylori<\/jats:italic>\n                      infection were added as indications. Serum pepsinogen level, endoscopic examination, and X\u2010ray examination were added to the diagnostic methods. The effects of 1\u2010week triple therapy consisting of potassium\u2010competitive acid blocker (P\u2010CAB), amoxicillin, and clarithromycin have improved, and high eradication rates can also be expected with proton pump inhibitors (PPI) or P\u2010CAB combined with amoxicillin and metronidazole. If the susceptibility test is not performed, the triple PPI or P\u2010CAB\/amoxicillin\/metronidazole therapy should be chosen, because the PPI\/amoxicillin\/metronidazole combination demonstrated a significantly higher eradication rate than PPI\/amoxicillin\/clarithromycin. In the proposal for gastric cancer prevention, we divided gastric cancer prevention measures by age from adolescent to elderly, who are at an increased gastric cancer risk, and presented measures for gastric cancer prevention primarily based on\n                      <jats:italic>H. pylori<\/jats:italic>\n                      eradication.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      We expect the revised guidelines to facilitate appropriate interventions for patients with\n                      <jats:italic>H. pylori<\/jats:italic>\n                      infection and accomplish its eradication and prevention of gastric cancer.\n                    <\/jats:p>\n                  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