{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T21:12:08Z","timestamp":1793913128843,"version":"4.8.0"},"reference-count":44,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,7,8]],"date-time":"2019-07-08T00:00:00Z","timestamp":1562544000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007819","name":"Allergan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007819","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Helicobacter"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p><jats:italic>Helicobacter pylori<\/jats:italic> selectively infects the human stomach, being the most prevalent chronic infection in the world. <jats:italic>H\u00a0pylori<\/jats:italic> presence causes chronic gastritis in 100% of infected patients and is the major cause of relevant diseases such as atrophic gastritis, peptic ulcer disease, and gastric cancer; it is for this reason that from a public health standpoint, it is considered a high\u2010impact pathogen, responsible of a significant morbidity and mortality. Nowadays, there are consensus and clinical guidelines regarding the infection management at a European level and in most of European countries, but no data have shown the level of implementation of these recommendations. The high costs that this infection carries both socially and to the health system require the continuous and systematic assessment of the diagnostic and treatment strategies, as well as the accessibility to diagnostic methods and most efficient drugs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To register the diagnosis, management strategies, and treatment of <jats:italic>H\u00a0pylori\u2010<\/jats:italic>infected adult patients in the Digestive Services outpatient clinics throughout Europe.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Noninterventionist prospective multicentre international Registry promoted by the <jats:italic>European Helicobacter and Microbiota Study Group<\/jats:italic>. National Coordinators will select recruiting gastroenterologists in their country that will register the <jats:italic>H\u00a0pylori\u2010<\/jats:italic>related routine clinical practice consultations they receive in an electronic case report form (e\u2010CRF) provided by AEG\u2010REDCap. Variables retrieved will include clinical, diagnostic, treatment, eradication confirmation, and outcome data. The database will allow researchers to perform specific subanalyses after approval by the Scientific Committee of the study.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hel.12630","type":"journal-article","created":{"date-parts":[[2019,7,8]],"date-time":"2019-07-08T07:14:26Z","timestamp":1562570066000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":79,"title":["Protocol of the European Registry on the management of <i>Helicobacter pylori<\/i> infection (Hp\u2010EuReg)"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1503-9085","authenticated-orcid":false,"given":"Adrian G.","family":"McNicholl","sequence":"first","affiliation":[{"name":"Gastroenterology Unit, Hospital Universitario de La Princesa, Instituto de Investigaci\u00f3n Sanitaria Princesa (IIS\u2010IP), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBEREHD) Universidad Aut\u00f3noma de Madrid Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colm A.","family":"O\u2019Morain","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine Trinity College Dublin Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2481-1612","authenticated-orcid":false,"given":"Francis","family":"Megraud","sequence":"additional","affiliation":[{"name":"Laboratoire de Bact\u00e9riologie H\u00f4pital Pellegrin Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2090-3445","authenticated-orcid":false,"given":"Javier P.","family":"Gisbert","sequence":"additional","affiliation":[{"name":"Gastroenterology Unit, Hospital Universitario de La Princesa, Instituto de Investigaci\u00f3n Sanitaria Princesa (IIS\u2010IP), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBEREHD) Universidad Aut\u00f3noma de Madrid Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"As Scientific Committee of the Hp\u2010Eureg on Behalf of the National Coordinators","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,7,8]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"1","article-title":"Schistosomes, liver flukes and Helicobacter pylori. 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