{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:33:55Z","timestamp":1787063635537,"version":"build-2736575974"},"reference-count":77,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2019,9,4]],"date-time":"2019-09-04T00:00:00Z","timestamp":1567555200000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Helicobacter"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    In the last year, many studies have demonstrated a potential role of\n                    <jats:italic>Helicobacter pylori<\/jats:italic>\n                    in the pathogenic mechanisms of different extragastric diseases. While the role of\n                    <jats:italic>H\u00a0pylori<\/jats:italic>\n                    in idiopathic thrombocytopenic purpura, idiopathic iron deficiency anemia, and vitamin B12 deficiency has already been demonstrated, there is growing evidence of other related conditions, especially cardiovascular, metabolic, and neurologic disorders, including neurodegenerative diseases. A summary of the results of the most relevant studies published over the last year on this attractive topic is presented in this review.\n                  <\/jats:p>","DOI":"10.1111\/hel.12636","type":"journal-article","created":{"date-parts":[[2019,9,5]],"date-time":"2019-09-05T02:01:39Z","timestamp":1567648899000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":73,"title":["Review:\n                    <i>Helicobacter pylori<\/i>\n                    and extragastric diseases"],"prefix":"10.1111","volume":"24","author":[{"given":"Francesco","family":"Franceschi","sequence":"first","affiliation":[{"name":"Emergency Medicine Fondazione Policlinico Universitario A. Gemelli IRCCS Universit\u00e0 Cattolica del Sacro Cuore Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcello","family":"Covino","sequence":"additional","affiliation":[{"name":"Emergency Medicine Fondazione Policlinico Universitario A. Gemelli IRCCS Universit\u00e0 Cattolica del Sacro Cuore Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Roubaud Baudron","sequence":"additional","affiliation":[{"name":"CHU Bordeaux P\u00f4le de G\u00e9rontologie Clinique Bordeaux France"},{"name":"University of Bordeaux INSERM U1053 BaRITOn Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,9,4]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2018.05.005"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2018.12.020"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2018.04.009"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2019.01.008"},{"key":"e_1_2_13_6_1","first-page":"426","article-title":"Microbes and Alzheimer\u2019 disease: lessons from H. pylori and gut 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