{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:07:55Z","timestamp":1791389275351,"version":"4.3.3"},"reference-count":45,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2020,9,12]],"date-time":"2020-09-12T00:00:00Z","timestamp":1599868800000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Helicobacter"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    New imaging techniques are still the topic of many evaluations for both the diagnosis of\n                    <jats:italic>Helicobacter pylori<\/jats:italic>\n                    gastritis and the detection of early gastric cancer. Concerning invasive tests, there were studies on the reuse of the rapid urease test material for other tests, and a novel fluorescent method to be used for histology but with limited sensitivity. Progress occurred essentially in the molecular methods area, especially next\u2010generation sequencing which is applied to detect both\n                    <jats:italic>H pylori<\/jats:italic>\n                    and the mutations associated with antibiotic resistance. For non\u2010invasive tests, a few studies have been published on the validity of breath collection bags, the shortening of the testing time, the performance of different analysers or the added value of citric acid in the protocol. The accuracy of serological immunochromatographic tests is also improving. Multiplex serology detecting antibodies to certain proteins allows confirmation of a current infection. Dried blood spots can be used to collect and store blood without a loss of accuracy. Finally, the serum antibody titer can be useful in predicting the risk of gastric cancer. Several stool antigen tests were evaluated with good results, and a novel test using immunomagnetic beads coated with monoclonal antibodies is potentially interesting. PCR detection in stools can also be effective but needs an efficient DNA extraction method. The use of easyMAG\n                    <jats:sup>\u00ae<\/jats:sup>\n                    (bioM\u00e9rieux) combined with Amplidiag\u00ae\n                    <jats:italic>H pylori<\/jats:italic>\n                    \u00a0+\u00a0ClariR (Mobidiag) appears to be powerful.\n                  <\/jats:p>","DOI":"10.1111\/hel.12735","type":"journal-article","created":{"date-parts":[[2020,9,28]],"date-time":"2020-09-28T03:10:52Z","timestamp":1601262652000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":75,"title":["Review: Diagnosis of\n                    <i>Helicobacter pylori<\/i>\n                    infection"],"prefix":"10.1111","volume":"25","author":[{"given":"Gauri","family":"Godbole","sequence":"first","affiliation":[{"name":"Gastrointestinal Pathogens Unit National Infection Service Public Health England London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis","family":"M\u00e9graud","sequence":"additional","affiliation":[{"name":"Inserm U1053 Bariton University of Bordeaux Bordeaux France"},{"name":"National Reference Centre for Campylobacters and Helicobacters Bacteriology Laboratory Pellegrin Hospital Bordeaux France <!--Query ID=\"q3\" Text=\"AUTHOR: Please check that authors and their affiliations are correct.\"-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilie","family":"Bess\u00e8de","sequence":"additional","affiliation":[{"name":"Inserm U1053 Bariton University of Bordeaux Bordeaux France"},{"name":"National Reference Centre for Campylobacters and Helicobacters Bacteriology Laboratory Pellegrin Hospital Bordeaux France <!--Query ID=\"q3\" Text=\"AUTHOR: Please check that authors and their affiliations are correct.\"-->"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,9,12]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/CM9.0000000000000486"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2019.06.024"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000501634"},{"key":"e_1_2_5_5_1","first-page":"1","article-title":"Linked color imaging and the Kyoto Classification of Gastritis: evaluation of visibility and inter\u2010rater reliability","author":"Takeda T","year":"2019","journal-title":"Digestion"},{"key":"e_1_2_5_6_1","first-page":"1993","article-title":"Blue laser magnifying endoscopy in the diagnosis of chronic gastritis","volume":"18","author":"Zhu Y","year":"2019","journal-title":"Exp Ther 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