{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T06:45:51Z","timestamp":1771051551321,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,11,24]],"date-time":"2021-11-24T00:00:00Z","timestamp":1637712000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Helicobacter"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p><jats:italic>Campylobacter concisus<\/jats:italic> is a Gram\u2010negative rod closely related to <jats:italic>Helicobacter pylori<\/jats:italic>. We sought to identify gastric biopsies positive for <jats:italic>C. concisus<\/jats:italic> that had been misdiagnosed as <jats:italic>H. pylori<\/jats:italic> gastritis in our routine surgical pathology practice.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>We performed a retrospective review of gastric biopsies in our regional microbiology and pathology electronic records to identify cases that were submitted for <jats:italic>H. pylori<\/jats:italic> testing in which <jats:italic>C. consicus<\/jats:italic> was identified on culture and how many had concurrent biopsies sent to pathology for histologic assessment over a two\u2010year period (2017\u20132018). Pathologic findings in the gastric biopsies were reviewed and immunohistochemical staining for <jats:italic>H. pylori<\/jats:italic> was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>50 of 2191\u00a0gastric biopsy specimens submitted to microbiology in 2017\u201318\u00a0grew <jats:italic>C. concisus<\/jats:italic> (2.3%), compared to 168 in which <jats:italic>H. pylori<\/jats:italic> was identified (7.7%). Twenty\u2010eight cases had concurrent histology. A total of four cases (three from 2017 and one from 2018) demonstrated organisms morphologically identical to <jats:italic>H. pylori<\/jats:italic> in the H&amp;E sections, of which all were <jats:italic>H. pylori<\/jats:italic> immunoreactive.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our case series is the first to demonstrate that <jats:italic>C. concisus<\/jats:italic> can mimic <jats:italic>H. pylori<\/jats:italic> gastritis in routine biopsy pathology.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hel.12864","type":"journal-article","created":{"date-parts":[[2021,11,25]],"date-time":"2021-11-25T13:11:52Z","timestamp":1637845912000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["<i>Campylobacter concisus<\/i> gastritis masquerading as <i>Helicobacter pylori<\/i> on gastric 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