{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T22:04:44Z","timestamp":1785017084541,"version":"3.55.0"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Helicobacter"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>We have previously reported that eradication therapy was more effective against <jats:italic>Helicobacter pylori (Hp)<\/jats:italic>\u2010negative gastric mucosa\u2010associated lymphoid tissue (MALT) lymphoma in non\u2010<jats:italic>Helicobacter pylori Helicobacter<\/jats:italic> (NHPH)\u2010positive cases than in NHPH\u2010negative cases and that the infection status of NHPH could be a predictive marker for the efficacy of eradication therapy for <jats:italic>H.\u00a0pylori<\/jats:italic> negative gastric MALT lymphoma. However, a diagnostic test for NHPH infection has not yet been clinically established. In this study, we investigated the endoscopic findings in cases of <jats:italic>H<\/jats:italic>.\u00a0<jats:italic>suis<\/jats:italic>\u2010infected gastritis associated with gastric MALT lymphoma reported at our institution.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Participants were selected from cases of gastric MALT lymphoma who underwent esophagogastroduodenoscopy at Hiroshima University Hospital, who were negative for the <jats:italic>API2<\/jats:italic>\u2010<jats:italic>MALT1<\/jats:italic>\u00a0gene, and who received eradication therapy as a first\u2010line treatment. We examined the endoscopic findings in nine cases from this group in which <jats:italic>H<\/jats:italic>.\u00a0<jats:italic>suis<\/jats:italic> infection was confirmed by polymerase chain reaction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Endoscopic findings, such as cracked mucosa, spotty redness, nodular gastritis\u2010like appearance, and white marbled appearance, which have been reported as characteristics of NHPH gastritis, were observed in multiple cases. The most common endoscopic findings in this study were cracked mucosa (7\/9 cases), followed by spotty redness (6\/9 cases), nodular gastritis\u2010like appearance (5\/9 cases), and white marbled appearance (2\/9 cases).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our study may serve as a reference for re\u2010evaluation of the diagnostic criteria for <jats:italic>H<\/jats:italic>.\u00a0<jats:italic>suis<\/jats:italic> infection and indications for eradication therapy, particularly for cases of <jats:italic>H.\u00a0pylori<\/jats:italic> negative gastric MALT lymphoma, where endoscopic findings such as those seen in this study were observed in the background mucosa.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hel.12887","type":"journal-article","created":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T19:09:41Z","timestamp":1648840181000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Investigation of endoscopic findings in nine cases of <i>Helicobacter suis<\/i>\u2010infected gastritis complicated by gastric mucosa\u2010associated lymphoid tissue lymphoma"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5729-0825","authenticated-orcid":false,"given":"Hiroki","family":"Kadota","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Metabolism Hiroshima University Hospital  Hiroshima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5038-1492","authenticated-orcid":false,"given":"Ryo","family":"Yuge","sequence":"additional","affiliation":[{"name":"Department of Endoscopy Hiroshima University Hospital  Hiroshima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryo","family":"Miyamoto","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Metabolism Hiroshima University Hospital  Hiroshima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rina","family":"Otani","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Metabolism Hiroshima University Hospital  Hiroshima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6369-0641","authenticated-orcid":false,"given":"Hidehiko","family":"Takigawa","sequence":"additional","affiliation":[{"name":"Department of Endoscopy Hiroshima University Hospital  Hiroshima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryohei","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Department of Endoscopy Hiroshima University 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