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Cellular senescence is an inducing factor for cancer occurrence and cellular senescence is an obvious phenomenon in gastric mucosal tissues of\n                      <jats:italic>H. pylori<\/jats:italic>\n                      \u2010positive CAG patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In this review, we collated the information on cellular senescence and\n                      <jats:italic>H. pylori<\/jats:italic>\n                      \u2010positive CAG.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At present, only a few studies have observed the effect of cellular senescence on precancerous lesions. In combination with the latest research, this review has collated the information on cellular senescence and\n                      <jats:italic>H. pylori<\/jats:italic>\n                      \u2010positive CAG from four aspects\u2010 telomere shortening, DNA methylation, increased reacive oxygen species (ROS) production, and failure of autophagy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This is expected to be helpful for exploring the relevant mechanisms underlying inflammatory cancerous transformation and formulating appropriate treatment strategies.<\/jats:p>\n                  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