{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T17:44:59Z","timestamp":1790185499502,"version":"4.1.0"},"reference-count":50,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T00:00:00Z","timestamp":1683072000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Helicobacter"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Recently, numerous publications on <jats:italic>Helicobacter pylori<\/jats:italic> (<jats:italic>H. pylori<\/jats:italic>) have been published, but bibliometric analyses on this research field are scarce. To address this gap, we conducted a bibliometric analysis to provide a comprehensive overview and to explore the current research states and hotspots in this field.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Publications on <jats:italic>H. pylori<\/jats:italic> from 2002 to 2021 were retrieved from the Web of Science Core Collection database (WoSCC). Trends in publications and citations were analyzed using Excel 2021. VOSviewer and Citespace were used to perform bibliometrics analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>36,266 publications on <jats:italic>H. pylori<\/jats:italic> were retrieved from the WoSCC database. In general, we observed an increasing trend in the number of publications over the past 20\u2009years. The United States was the most productive and influential country, with the largest proportion of both publications and total citations. <jats:italic>Helicobacter<\/jats:italic>, <jats:italic>US Department of Veterans Affairs<\/jats:italic>, and <jats:italic>Graham, David<\/jats:italic> were the most productive journals, institutions and authors, respectively. Further analysis the co\u2010occurrence and burst detection of keywords revealed that the most common keywords were \u201c<jats:italic>Helicobacter pylori,<\/jats:italic>\u201d \u201cgastric cancer,\u201d and \u201cgastritis,\u201d all keywords were divided into eight main clusters, and the most important current research hotspot was the relationship between <jats:italic>H. pylori<\/jats:italic> infection and the changes of gut microbiota.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The United States has been the most productive and influential country on <jats:italic>H. pylori<\/jats:italic> research, and <jats:italic>H. pylori<\/jats:italic>\u2010related research remains an active research field. The relationship between <jats:italic>H. pylori<\/jats:italic> infection and the changes of gut microbiota is a research hotspot attracting significant attention.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hel.12986","type":"journal-article","created":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T14:59:11Z","timestamp":1683125951000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["States and hotspots in <i>Helicobacter pylori<\/i> research from 2002 to 2021: A bibliometric analysis"],"prefix":"10.1111","volume":"28","author":[{"given":"Ruiyu","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Gastroenterology The Affiliated Hospital of Southwest Medical University  Luzhou China"},{"name":"Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province  Luzhou 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Southwest Medical University  Luzhou China"},{"name":"Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province  Luzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xian","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology The Affiliated Hospital of Southwest Medical University  Luzhou China"},{"name":"Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province  Luzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6064-0526","authenticated-orcid":false,"given":"Xiaowei","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology The Affiliated Hospital of Southwest Medical University  Luzhou China"},{"name":"Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province  Luzhou 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