{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T22:13:57Z","timestamp":1790633637608,"version":"4.1.0"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T00:00:00Z","timestamp":1776124800000},"content-version":"vor","delay-in-days":44,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","award":["101101252"],"award-info":[{"award-number":["101101252"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","award":["101162959"],"award-info":[{"award-number":["101162959"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Helicobacter"],"published-print":{"date-parts":[[2026,3]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n Gastric cancer continues to impose a substantial health burden in Europe. The European Council Recommendations have called for consideration of implementing measures aimed at reducing gastric cancer\u2010related mortality.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n This manuscript reviews current gastric cancer prevention initiatives in Europe. The GISTAR study in Latvia has been enrolling participants from the general population for\n \n Helicobacter pylori<\/jats:italic>\n <\/jats:styled-content>\n screen\u2010and\u2010treat intervention together with serological testing for pepsinogens. The EUROHELICAN study was the first to evaluate an\n \n H. pylori<\/jats:italic>\n <\/jats:styled-content>\n screen\u2010and\u2010treat strategy in young adults, which has been expanded within the TOGAS project. In addition, TOGAS has addressed stakeholder perspectives, the cost\u2010effectiveness of screen\u2010and\u2010treat strategies, and the prevalence of gastric precancerous conditions among individuals participating in colorectal cancer screening. The GISTAR cohort has also enabled the assessment of long\u2010term outcomes following\n \n H. pylori<\/jats:italic>\n <\/jats:styled-content>\n eradication. The EUGastScreen project, carried out within the EUCanScreen Joint Action, aims to evaluate the feasibility of simultaneous screening for\n \n H. pylori<\/jats:italic>\n <\/jats:styled-content>\n infection and colorectal cancer using a stool\u2010based test. The European Registry on\n \n H. pylori<\/jats:italic>\n <\/jats:styled-content>\n Management (Hp\u2010EuReg) supports the collection of important clinical data from routine clinical practice. Furthermore, the development of European guidelines for gastric cancer prevention has been initiated as part of the European Commission Initiative on Gastric Cancer and is expected to continue until 2027. The recently published 5th edition of the European Code Against Cancer includes recommendations on\n \n H. pylori<\/jats:italic>\n <\/jats:styled-content>\n management for the first time.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Ongoing initiatives will provide important evidence to support the future implementation of gastric cancer prevention strategies, including data on feasibility, acceptability among the general population and stakeholders, and cost\u2010effectiveness. However, additional implementation studies for gastric cancer prevention will be required.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/hel.70126","type":"journal-article","created":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T05:02:11Z","timestamp":1776229331000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Overview of Gastric Cancer Prevention Initiatives in Europe"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0319-8855","authenticated-orcid":false,"given":"Marcis","family":"Leja","sequence":"first","affiliation":[{"name":"Institute of Clinical and Preventive Medicine University of Latvia Riga Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3069-0140","authenticated-orcid":false,"given":"Danute","family":"Ra\u017euka\u2010Ebela","sequence":"additional","affiliation":[{"name":"Institute of Clinical and Preventive Medicine University of Latvia Riga Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5616-4333","authenticated-orcid":false,"given":"Bojan","family":"Tepes","sequence":"additional","affiliation":[{"name":"National Institute for Public Health Ljubljana Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8673-3122","authenticated-orcid":false,"given":"Jan","family":"Bornschein","sequence":"additional","affiliation":[{"name":"Institute of Clinical and Preventive Medicine University of Latvia Riga Latvia"},{"name":"Medical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), Radcliffe Department of Medicine University of Oxford, John Radcliffe Hospital\/Headley Way Oxford UK"},{"name":"Translational Gastroenterology and Liver Unit, Nuffield Department of Experimental Medicine University of Oxford, John Radcliffe Hospital\/Headley Way Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0121-6850","authenticated-orcid":false,"given":"M\u00e1rio Dinis","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Precancerous Lesions and Early Cancer Management Group, Research Center of IPO Porto (CI\u2010IPOP)\/CI\u2010IPOP@RISE (Health Research Group), Portuguese Institute of Oncology of Porto (IPO Porto)\/Porto Comprehensive Cancer Center (Porto.CCC) Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0780-6261","authenticated-orcid":false,"given":"Tamara Matysiak","family":"Budnik","sequence":"additional","affiliation":[{"name":"Nantes University Hospital Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jochen","family":"Weigt","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hepatology, and Infectious Diseases Otto von Guericke University Magdeburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9646-2052","authenticated-orcid":false,"given":"Viktoria","family":"Knaze","sequence":"additional","affiliation":[{"name":"Early Detection, Prevention, and Infections Branch International Agency for Research on Cancer (IARC) Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colm","family":"O'Morain","sequence":"additional","affiliation":[{"name":"Beacon Hospital, Beacon Court Dublin Ireland"},{"name":"Faculty of Health Sciences Trinity College Dublin Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7226-322X","authenticated-orcid":false,"given":"Duco T.","family":"M\u00fclder","sequence":"additional","affiliation":[{"name":"Department of Public Health Erasmus University Medical Center Rotterdam the 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