{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T02:21:44Z","timestamp":1788142904106,"version":"build-2803163510"},"reference-count":46,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2013,5,15]],"date-time":"2013-05-15T00:00:00Z","timestamp":1368576000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hepatology Research"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:p>Nodular regenerative hyperplasia (<jats:styled-content style=\"fixed-case\">NRH<\/jats:styled-content>) and hepatoportal sclerosis, also known as obliterative portal venopathy (<jats:styled-content style=\"fixed-case\">OPV<\/jats:styled-content>), are two causes of non\u2010cirrhotic portal hypertension (<jats:styled-content style=\"fixed-case\">NCPH<\/jats:styled-content>).<jats:styled-content style=\"fixed-case\">NCPH<\/jats:styled-content>is an increasingly recognized entity that can be seen in association with collagen vascular diseases and with the use of medications such as azathioprine and didanosine, but oftentimes the etiology remains unidentified. We herein report a case of<jats:styled-content style=\"fixed-case\">NCPH<\/jats:styled-content>occurring due to<jats:styled-content style=\"fixed-case\">OPV<\/jats:styled-content>and<jats:styled-content style=\"fixed-case\">NRH<\/jats:styled-content>in a 64\u2010year\u2010old woman with myasthenia gravis (<jats:styled-content style=\"fixed-case\">MG<\/jats:styled-content>), status post\u2010thymectomy. Portal hypertension was diagnosed incidentally on computed tomography in the absence of predisposing factors. Extensive work\u2010up to determine the etiology of any underlying liver disease was unrevealing.<jats:styled-content style=\"fixed-case\">NRH<\/jats:styled-content>and<jats:styled-content style=\"fixed-case\">OPV<\/jats:styled-content>were identified on liver biopsy. Subsequently, the patient had variceal bleeding that necessitated transjugular intrahepatic portosystemic shunt placement. A few similar cases of<jats:styled-content style=\"fixed-case\">NCPH<\/jats:styled-content>occurring in the setting of<jats:styled-content style=\"fixed-case\">MG<\/jats:styled-content>have been previously reported, suggesting that the immunological mechanisms involved in the pathogenesis of myasthenia may also have contributed to the development of<jats:styled-content style=\"fixed-case\">NCPH<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/hepr.12045","type":"journal-article","created":{"date-parts":[[2013,5,16]],"date-time":"2013-05-16T03:45:24Z","timestamp":1368675924000},"page":"999-1003","source":"Crossref","is-referenced-by-count":11,"title":["Hepatoportal sclerosis (obliterative portal venopathy) and nodular regenerative hyperplasia in a patient with myasthenia gravis: A case report and review of the published work"],"prefix":"10.1111","volume":"43","author":[{"given":"Manasi","family":"Agrawal","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Division of Gastroenterology Maimonides Medical Center Brooklyn"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rabin","family":"Rahmani","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Division of Gastroenterology Maimonides Medical Center Brooklyn"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiran","family":"Nakkala","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Division of Gastroenterology Maimonides Medical Center Brooklyn"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Isabel","family":"Fiel","sequence":"additional","affiliation":[{"name":"Department of Pathology Mount Sinai School of Medicine New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Schiano","sequence":"additional","affiliation":[{"name":"Division of Liver Diseases Mount Sinai School of Medicine New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,5,15]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1746.2002.02596.x"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-196510000-00006"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2010.07.038"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.24422"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01211199"},{"key":"e_1_2_4_7_1","first-page":"163","article-title":"Non\u2010specific immunological abnormalities and association of autoimmune diseases in idiopathic portal hypertension. 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