{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T06:52:17Z","timestamp":1775890337381,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,5,11]],"date-time":"2016-05-11T00:00:00Z","timestamp":1462924800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hepatology Research"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:sec><jats:title><jats:italic>Aim<\/jats:italic><\/jats:title><jats:p>Portal hypertension has recently been implicated in the pathogenesis of small\u2010for\u2010size syndrome (SFSS) in adult\u2010to\u2010adult living\u2010donor liver transplantation (A\u2010LDLT). The aim of our study is to compare the portal venous pressure (PVP) cut\u2010off values of 15\u00a0mmHg and 20\u00a0mmHg in terms of prevention of SFSS in A\u2010LDLT.<\/jats:p><\/jats:sec><jats:sec><jats:title><jats:italic>Methods<\/jats:italic><\/jats:title><jats:p>Seventy\u2010six patients underwent A\u2010LDLT. A PVP &lt;20\u00a0mmHg at the end of the operation was targeted using graft inflow modulation. Patients were divided into two groups: group A, final PVP &lt;15\u00a0mmHg; and group B, final PVP 15\u201319\u00a0mmHg. Peak serum bilirubin and peak international normalized ratio in the first month after A\u2010LDLT, as well as hepatic encephalopathy, SFSS, 90\u2010day morbidity, and mortality were observed in both groups.<\/jats:p><\/jats:sec><jats:sec><jats:title><jats:italic>Results<\/jats:italic><\/jats:title><jats:p>Final PVP was well controlled below 20\u00a0mmHg in all patients (group A, <jats:italic>n<\/jats:italic>\u2009=\u200939; group B, <jats:italic>n<\/jats:italic>\u2009=\u200937). Six patients suffered SFSS in group B (16.2%) compared to one patient (2.6%) in group A (<jats:italic>P<\/jats:italic>\u2009=\u20090.04). Nine patients died in group B (24.3%), four of whom died of SFSS, compared to three patients in group A (7.7%) (<jats:italic>P<\/jats:italic>\u2009=\u20090.047).<\/jats:p><\/jats:sec><jats:sec><jats:title><jats:italic>Conclusion<\/jats:italic><\/jats:title><jats:p>A PVP cut\u2010off of 15\u00a0mmHg seems to be a more appropriate target level than a cut\u2010off of 20\u00a0mmHg for prevention of postoperative SFSS in A\u2010LDLT.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hepr.12727","type":"journal-article","created":{"date-parts":[[2016,4,16]],"date-time":"2016-04-16T03:14:44Z","timestamp":1460776484000},"page":"293-302","source":"Crossref","is-referenced-by-count":21,"title":["A portal pressure cut\u2010off of 15 versus a cut\u2010off of 20 for prevention of small\u2010for\u2010size syndrome in liver transplantation: A comparative study"],"prefix":"10.1111","volume":"47","author":[{"given":"Ayman M.A.","family":"Osman","sequence":"first","affiliation":[{"name":"Department of General Surgery, Unit of Hepatobiliary Surgery, Faculty of Medicine Cairo University  Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adel A.","family":"Hosny","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Unit of Hepatobiliary Surgery, Faculty of Medicine Cairo University  Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mostafa A.","family":"El\u2010Shazli","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Unit of Hepatobiliary Surgery, Faculty of Medicine Cairo University  Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinji","family":"Uemoto","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Hepato\u2010Pancreatico-Biliary Surgery and Transplantation, Graduate School of Medicine Kyoto University  Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Abdelaziz","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, Faculty of Medicine Cairo University  Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayman S.","family":"Helmy","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Unit of Hepatobiliary Surgery, Faculty of Medicine Cairo University  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