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Furthermore, hyponatremia, spontaneous bacterial translocation and hepatorenal syndrome also greatly worsen the prognosis. Effective treatment of cirrhotic ascites improves the quality of life and survival rate. Recently, the newly produced diuretic, tolvaptan (vasopressin V2 receptor antagonist), was reported to be effective in the treatment of refractory ascites in liver cirrhosis; however, there has not been an associated positive effect on the prognosis. There are various types of treatment for ascites, such as large\u2010volume paracenteses, a cell\u2010free and concentrated ascites reinfusion therapy, a transjugular intrahepatic portosystemic shunt, and a peritoneo\u2010venous shunt. Although they improve the prognosis, liver transplantation remains the ultimate form of treatment. The present article discusses the therapeutic management of cirrhotic ascites.<\/jats:p>","DOI":"10.1111\/hepr.12769","type":"journal-article","created":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T10:55:51Z","timestamp":1467370551000},"page":"166-177","source":"Crossref","is-referenced-by-count":20,"title":["Treatment for cirrhotic ascites"],"prefix":"10.1111","volume":"47","author":[{"given":"Hideto","family":"Kawaratani","sequence":"first","affiliation":[{"name":"Third Department of Internal Medicine Nara Medical University  Kashihara, Nara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Fukui","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine Nara Medical University  Kashihara, Nara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitoshi","family":"Yoshiji","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine Nara Medical University  Kashihara, 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