{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,26]],"date-time":"2025-08-26T07:04:41Z","timestamp":1756191881752},"reference-count":27,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2017,2,6]],"date-time":"2017-02-06T00:00:00Z","timestamp":1486339200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hepatology Research"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>The indocyanine green (ICG) finger\u2010piece method (FPM), which allows measurement of the ICG concentration by mounting a light sensor onto a finger, is used to assess liver function. We compared the ICG FPM with the conventional ICG blood sampling method (BSM) in patients with liver disorders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Ninety consecutive patients simultaneously underwent the ICG BSM and ICG FPM. After ICG administration, blood samples were collected at 5, 10, and 15\u00a0min for the ICG BSM. The ICG concentration was measured through the finger piece by an ICG clearance meter.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seventy\u2010one patients (78.9%) had Child\u2013Pugh class A liver disease, and 19 (21.1%) had class B or C. The FPM\u2010measured ICG plasma disappearance rate was positively correlated with the BSM\u2010measured values (<jats:italic>r<\/jats:italic>\u2009=\u20090.886, <jats:italic>P<\/jats:italic>\u2009&lt;\u00a00.001). Bland\u2013Altman analysis showed good agreement between the two methods (mean difference, 0.012\u2009\u00b1\u20090.018). The FPM\u2010measured ICG plasma disappearance rate was positively correlated with the BSM\u2010measured values both in patients with Child\u2013Pugh class A liver disease (<jats:italic>r<\/jats:italic>\u2009=\u20090.821, <jats:italic>P<\/jats:italic>\u2009&lt;\u00a00.001) and class B or C liver disease (<jats:italic>r<\/jats:italic>\u2009=\u20090.859, <jats:italic>P<\/jats:italic>\u2009&lt;\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The ICG FPM may be an alternative to the ICG BSM for liver function assessment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hepr.12858","type":"journal-article","created":{"date-parts":[[2016,12,26]],"date-time":"2016-12-26T07:56:41Z","timestamp":1482739001000},"page":"1235-1240","source":"Crossref","is-referenced-by-count":8,"title":["Use of finger\u2010piece method for indocyanine green clearance 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